نتایج جستجو برای: donor graft quality
تعداد نتایج: 889993 فیلتر نتایج به سال:
Introduction This section deals with surgical issues that may potentially complicate the immediate post-transplant period. Many of these issues, particularly ones that arise in patient selection can have a very important impact on the immediate post-operative course of the patient and some can have far reaching consequences for long-term graft and patient survival. Donor-recipient matching refe...
Graft rejection in allogeneic bone marrow transplantation (BMT) can occur when donor and recipient are mismatched at one or more major histocompatibility complex (MHC) loci. Donor T cells can prevent graft rejection, but may cause fatal graft-versus-host disease (GVHD). We tested whether irradiation of allogeneic donor lymphocytes would preserve their graft-facilitating activity while inhibitin...
Numerous experimental models have demonstrated that graft-vs.-host disease (GVHD) does not occur in irradiation chimeras when the graft does not contain mature, immunocompetent T lymphocytes, but clinical studies have shown that T cell depletion of donor marrow can be associated with a greatly increased risk of graft failure. We have developed a model where engraftment of (C57BL/6J x C3H/HeJ)F1...
Every four hours, a patient dies awaiting a liver transplant.1 This is a stark reality, whether it’s your father, your wife, your best friend, or one of your favorite patients. The organ shortage continues unabated, and the quality of the average donor gets worse with each passing year. It is in this context that patients and transplant professionals are faced with the increasingly difficult de...
Donor-recipient ABO blood group mismatching is associated with a decreased graft survival rate in liver transplantation. We have been unable to demonstrate an effect of high levels of panel reactive antibody or a positive donor-specific cytotoxic antibody cross-match on graft survival. A limited analysis of HLA-matching for the A, B, and DR loci suggests a paradoxical effect, but much more expe...
PURPOSE To determine the fate of donor epithelial, stromal, and endothelial cells after corneal transplantation in humans. METHODS Fifty-two transplanted corneal buttons were explanted over a 2-year period from patients who required regrafting and had received corneas from donors of opposite sex. Fluorescence in situ hybridization of the sex chromosomes of the epithelial, stromal, and endothe...
Situs inversus totalis (SIT) is a rare congenital anomaly, and liver transplantation (LT) in an adult SIT patient is extremely rare. Liver transplantation in a SIT patient is also technically challenging due to reversed anatomical structures. Here we present the case of an 18-year-old female with SIT in whom left lobe living donor LT was performed. The patient suffered from cirrhosis due to aut...
BACKGROUND Although the outcomes of transplantation with expanded criteria donor (ECD) kidneys are inferior to non-ECD transplants in the USA, the impact of the ECD classification on Canadian kidney transplant recipients is not known. OBJECTIVES The objective of the study was to assess the performance of the US-derived ECD classification among deceased donor kidney transplant recipients in a ...
Conventional open harvest of the great saphenous vein (GSV) during CABG results in approximately 7% donor-site complications. Using endoscopic vein harvesting (EVH) the full GSV length can be harvested through a 3 cm incision. This nonsystematic review discusses several key issues concerning EVH, based on an extensive Pubmed search. Found studies show that EVH results in reduced number of wound...
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