CONTEXT AND OBJECTIVE Knowledge of the reasons for donor deferral can help in planning more efficient recruitment strategies and evaluating donor selection criteria. This study aimed to investigate the rates and reasons for donor deferral. DESIGN AND SETTING Retrospective study at Shiraz Blood Transfusion Center, Shiraz, Iran. METHODS 141,820 volunteers were interviewed confidentially by ph...

BACKGROUND The European Eye Bank Association (EEBA) is a technical-scientific organization for eye banks. Founded in 1989 with the simple objective of sharing information on eye banking, the Association is today the leading pan-national association in Europe dedicated to the advancement of eye banking and an authoritative reference point for eye banks which work according to quality standards. ...

Although the value of HLA matching for the selection of platelet donors for patients refractory to random platelets is beyond doubt, even perfectly matched combinations sometimes fail to give a satisfactory transfusion response. With HLA typing and negative lymphocytotoxicity crossmatches, 35% of the platelet transfusions administered to 15 patients gave disappointing results (29 of 82). Additi...

Background: Nowadays, gamete and embryo donation is applied as effective process in treatment infertility problems. In order to participate in the process of donation, donors should complete an extensive questionnaire that details their personal and family medical history. Included in this questionnaire should be a detailed sexual history, substance abuse history, history of family disease, and...

1.0 INTENDED USE: For the qualitative and semiquantitative detection of human IgG antibodies to measles virus in human serum by enzyme immunoassay. Individual serum specimens may be used for the determination of immune status. Paired (acute / convalescent) sera, may be used to demonstrate seroconversion or significant rises in antibody level, as an aid in the diagnosis of primary infection. Thi...

To construct a semen bank, the collection of donated semen has to be done and an important concern is the safety of collected semen. The contamination is a big problem. Basically, the infectious pathogens can exist within donated semen, hence, a good donor screening is very important. Although viruses have an indirect role in sperm quality, but the evidence in banked semen is presently lack. Th...

The World Health Organisation has estimated that 10 million adults and one million children are infected with HIV worldwide.' Most of these infections will have been acquried through heterosexual contact and the increasing prevalence of HIV infection among women has implications for children as vertical transmission from mother to child is the major route by which children acquire infection. Th...

Schizosaccharomyces pombe cells switch mating type by replacing genetic information at the expressed mat1 locus with sequences copied from mat2-P or mat3-M silent donor loci. The choice of donor locus is dictated by cell type, such that mat2 is the preferred donor in M cells and mat3 is the preferred donor in P cells. Donor choice involves a recombination-promoting complex (RPC) containing Swi2...

TRALI is considered a serious hazard among immune complications of blood transfusion and its occurrence is admitted to be globally underestimated. Each type of blood product is likely to cause TRALI. We report here on two consecutive observations of TRALI caused by red blood cell concentrates, in which anti-HLA class I and class II antibodies resulting from post-gravitational allo-immunization ...