Objective- To evaluate the total toxic dose of lidocaine and serum lidocaine concentrations resulting in clinical signs of toxicity in chickens. Design- Experimental study Animals- Eight healthy, female, 55-week-old chickens (Lohman breed) weighing 1.45 ± 0.17 kg (mean ± SD) Procedure- A loading dose of 2% lidocaine (4 mg/kg) was administered IV, followed by a constant-rate infusion at a dose o...

Since their initial description, phased array coils have become increasingly popular due to their ease of customization for various applications. Numerous methods for combining data from individual channels have been proposed that attempt to optimize the SNR of the resultant images. One issue that has received comparatively little attention is how to apply these combination techniques to a seri...

When a resting enzyme is activated, substrate concentration profile evolves in its vicinity, ultimately tending to steady state. We use modern theories for many-body effects on diffusion-influenced reactions to derive approximate analytical expressions for the steady-state profile and the Laplace transform of the transient concentration profiles. These show excellent agreement with accurate man...

The folding pathways of some proteins include the population of partially structured species en route to the native state. Identification and characterization of these folding intermediates are particularly difficult as they are often only transiently populated and play different mechanistic roles, being either on-pathway productive species or off-pathway kinetic traps. To define the role of fo...

background: presently, the british-american tobacco company (bat) located in ibadan, oyo state is the only tobacco producing company in nigeria accounting for about nine different brands of cigarette tobacco smoked in the country. the tobacco leaves are produced from some farmlands located in oke-ogun area of ibadan where special fertilizers are used for the growing of the tobacco leaves. the u...

background: natural radiation is constantly present in the environment and is emitted from a variety of natural and artificial sources. it affects human body and environment. materials and methods: the activity concentrations of 238u, 232th and 40k have been determined by gamma ray spectrometer with an hpge detector in sediments of cauvery river, tamilnadu, india. results: the absorbed dose rat...

background: natural radionuclides are always present in the environment. human exposure to the background radiation is inevitable. it is therefore important to assess health risk associated with these radionuclides. materials and methods: the distribution of natural radionuclides 238u, 232th and 40k in soil samples collected from all the twenty (20) local governments headquarter areas in ogun s...

background: an effective polymer gel dosimeter can be fabricated by varying the composition of its chemical components. materials and methods: the magat gel dosimeter formulations that used different compositions of methacrylic acid (maa) and gelatin were extensively investigated in the present study according to the r2–dose response and r2–dose sensitivity. the irradiation of magat gel was per...