PURPOSE To analyze the optimum organ filling point for organs at risk (OARs) dose in cervical cancer high-dose-rate (HDR) brachytherapy. MATERIAL AND METHODS In a retrospective study, 32 locally advanced cervical cancer patients (97 insertions) who were treated with 3D conformal external beam radiation therapy (EBRT) and concurrent chemotherapy during 2010-2013 were included. Rotterdam HDR ta...

BACKGROUND Radiation-induced lung injury (RILI) is an important dose-limiting toxicity during thoracic radiotherapy. The purpose of this study is to investigate single photon emission computed tomography (SPECT) perfusion-weighted functional dose-volume histogram (FDVH) for predicting RILI in non-small cell lung cancer (NSCLC) patients treated with definitive chemoradiotherapy. METHODS Fifty-...

During radiotherapy for gastric lymphoma, it is difficult to protect the liver and kidneys in cases where there is considerable overlap between these organs and the target volume. This study was conducted to compare the three radiotherapy planning techniques of four-fields 3D conformal radiotherapy (3DCRT), half-field radiotherapy (the half-beam method) and intensity-modulated radiotherapy (IMR...

The SAVI (the Strut Adjusted Volume Implant) device is one of the most novel devices used in Accelerated Partial Breast Irradiation (APBI). Various dosimetric parameters, as well as doses to adjacent critical structures, have been evaluated in 121 patients in this single institution 5-year retrospective study, using dose volume histogram (DVHs): Coverage Index (CI), cavity and planning target v...

Successful treatment planning in radiation therapy depends in part on understanding the spatial relationship between patient anatomy and the distribution of radiation dose. We present several visualizations based on volume rendering that offer potential solutions to this problem. The visualizations employ region boundary surfaces to display anatomy, polygonal meshes to display treatment beams, ...

Introduction: The present study evaluated the dosimetric comparison between 6MV flattened filter (FF) and flattening filter-free (FFF) photon beams in intensity-modulated radiation therapy (IMRT) technique for the treatment of glioblastoma (GBM) patients. Material and Methods: The present study was conducted on 10 patients with GBM previously...

Structural and morphometric features of thyroid C and follicular cells were studied in adult rat females after treatment with synthetic salmon calcitonin (CT). The animals were chronically treated with either a low (10 IU/kg b.w) or a high (100 IU/kg b.w) dose of CT. A stereological method was applied to determine the volume density and the number of immunoreactive C cells. The height and volum...

BACKGROUND Lung cancer patients are often in poor physical condition, and a shorter treatment time would reduce their discomfort. Dynamic conformal arc therapy (DCAT) offers a shorter treatment time than conventional 3D conformal radiotherapy (3D CRT) and is usually available even in departments without inverse planning possibilities. We examined its suitability as a treatment modality for lung...

Introduction: Presence of dental filling material (DFM) such as amalgam in treatment patient with nasopharyngeal cancer (NPC) is common. Streaking artifact Arising from this high density material in computed tomography (scan), may lead to perturbation in dose calculation and dose delivery. Widespread performance of intensity-modulated radiotherapy (IMRT) for NPC using anterior...

PURPOSE High intensity focused ultrasound (HIFU) is a non-invasive therapeutic technique that can thermally ablate tumors. Boiling histotripsy (BH) is a HIFU approach that can emulsify tissue in a few milliseconds. Lesion volume and temperature effects for different BH sonication parameters are currently not well characterized. In this work, lesion volume, temperature distribution, and area of ...