INTRODUCTION Commensal E. coli can be considered a reservoir of genes coding for antibiotic resistance that may be transmitted in hospitals by healthcare workers (HCWs). This study aimed to determine the fecal carriage rate of extended-spectrum β-lactamase (ESBL)-producing E. coli among HCWs. METHODOLOGY Stool samples were collected from 200 HCWs. Phenotypic screening for ESBL and AmpC β-lact...

Antibiotic resistance among uropathogens causing community acquired urinary tract infection (CAUTI) is increasing worldwide. Severity and endemicity persists despite of wide spread availability of drugs. Knowledge of the aetiology and antimicrobial susceptibility patterns of uropathogens is important in order to determine the best empiric treatment option. Extended-spectrum beta-lactamase (ESBL...

Sulmonellu organisms occur worldwide and are responsible for a broad spectrum of clinical syndromes, including self-limited gastroenteritis, bacteremia and vascular infection, enteric fever, and metastatic focal infections, although infection may be asymptomatic.’ Here we report a case of subcutaneous abscess caused by multiresistant Salmonella senftenberg. A 62-year-old obese female presented ...

BACKGROUND Pseudomonas aeruginosa is an opportunistic pathogen associated with nosocomial infections. The emergence and dissemination of metallo-beta-lactamases (MBLs) has contributed to the high rate of resistance among P. aeruginosa isolates. OBJECTIVES The purpose of this study was to describe the prevalence and the clonal dissemination of MBL- producing P. aeruginosa isolates collected fr...

Resistance to broad spectrum β lactams, mediated by extended spectrum beta lactamase (ESβL) and AmpC βL enzymes is fast spreading in Nigerian hospitals. Production of these enzymes has resulted in treatment failure especially if one of the second or third generation cephalosporins is used. A study was undertaken to determine the prevalence of each enzyme and coproduction of the two enzymes amon...

BACKGROUND & OBJECTIVES Carbapenemase-producing Enterobacteriaceae isolates have been increasingly identified worldwide. Though molecular data regarding New Delhi metallo-beta-lactamase-1 (NDM-1) producers are available, data regarding their rate of infection in a hospital setting and percentage among different clinical isolates are scarce. Hence, this study was undertaken to determine the occu...

BACKGROUND Resistance to contemporary broad-spectrum beta-lactams, mediated by extended-spectrum beta-lactamases (ESBL), is an increasing problem worldwide. Many of the emerging antimicrobial resistance problems of this decade have been characterized by difficulty in the recognition of resistance in the laboratory, particularly by rapid susceptibility test methods. The plasmid-encoded ESBL repr...

BACKGROUND Extended-spectrum β-lactamases (ESBLs) is one of the most important mechanisms of resistance to β-lactams especially among Enterobacteriaceae family including Klebsiella spp. Different types of extended-spectrum β-lactamases including CTX-M-type and PER enzymes are identified among gram negative bacteria. OBJECTIVES The current study aimed to determine the prevalence of CTX-M-type ...

Results of a 2003 survey carried out in Italy to evaluate the prevalence of extended-spectrum beta-lactamase (ESBL)-producing enterobacteria are presented. Eleven Italian Microbiology Laboratories investigated 9,076 consecutive nonreplicate isolates (inpatients, 6,850; outpatients, 2,226). ESBL screening was performed by MIC data analysis. Confirmation was obtained using the double-disk synergy...

background and objectives : the rapid emergence and dissemination of carbapenemase-producing klebsiella pneumoniae strains and other members of the enterobacteriaceae poses a considerable threat to the care of hospitalized patients and to public health. the aim of this study was to determine the frequency of metallo-β-lactamases (mbl) and vim-1 gene in multidrug-resistant strains of k. pneumoni...