background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...

two steps synthetic method for the preparation of a novel emulsion stabilizer called poly(ricineoleic acid-b-ethyleneglycol-b-ricineoleic acid) with average mass molecular weight of 7000 daltons is investigated. in the first step, oligoricineoleic acid with average mass molecular weight of 1800 daltons is synthesized (yield 70%). in the second step, the desired copolymer is  synthesized from th...

the oil refining industries are using a number of demulsifiers for dewatering and desalination of crude oil but experience has shown that universal demulsifiers can not be produced. each kind of water in oil (w/o) emulsion requires specific by composition demulsifier. in practice, synergetic effect of the interaction between different types of demulsifiers is often sought. for dewatering the w...

Background: Intravenous drug delivery is an advantageous choice for rapid administration, immediate drug effect, and avoidance of first-pass metabolism in oral drug delivery. In this study, the synthesis, formulation, and characterization of atorvastatin-loaded polyurethane (PU) nanoparticles were investigated for intravenous route of administration. Method: First, PU was synthesized and charac...

A novel concept of stabilizing multiple-phase food structure such as emulsion using solely the constitutional bacteria enables an all-natural grade formulation and thus a clean label declaration. In this paper, we propose efficient approach to hydrophobically modifying surface lactic acid Lactobacillus rhamnosus (LGG) lauroyl ahloride (LC) in non-aqueous media. Compared unmodified bacteria, cel...