The Drosophila decapentaplegic (dpp) gene, encoding a secreted protein of the transforming growth factor-beta (TGF-beta) superfamily, controls proliferation and patterning in diverse tissues, including the eye imaginal disc. Pattern formation in this tissue is initiated at the posterior edge and moves anteriorly as a wave; the front of this wave is called the morphogenetic furrow (MF). Dpp is r...

OBJECTIVE Dipeptidyl peptidase IV (DPP IV/CD26) is involved in the degradation of proline-rich proteins such as gliadin and in modulation of the immune response. The aim of this study was to examine the possible causal connection between DPP IV enzyme activities and celiac disease (CD) in children. PATIENTS AND METHODS Intestinal mucosal biopsy specimens were obtained from 97 patients. The pa...

The type beta transforming growth factor family is composed of a series of processed, secreted growth factors, several of which have been implicated in important regulatory roles in cell determination, inductive interactions, and tissue differentiation. Among these factors, the sequence of the DPP protein from Drosophila is most similar to two of the vertebrate bone morphogenetic proteins, BMP2...

In 1953 A. Grothendieck introduced the property known as Dunford-Pettis property [18]. A Banach space X has the Dunford-Pettis property (DPP in the sequel) if whenever (xn) and (ρn) are weakly null sequences in X and X∗, respectively, we have ρn(xn) → 0. It is due to Grothendieck that every C(K )-space satisfies the DPP. Historically, were Dunford and Pettis who first proved that L1(μ) satisfie...

Dipeptidyl peptidase-4 inhibitors (DPP-4Is) inhibit the inactivation of incretin hormones while also affecting the immune system, since CD26/DPP-4 is involved in immune regulation. The current study shows that the use of DPP-4Is as therapy for type 2 diabetes patients may induce joint symptoms with decrease in plasma SDF-1α level.

BACKGROUND Endothelial dysfunction is an independent predictor for cardiovascular events in patients with type 2 diabetes (T2DM). Glucagon like peptide-1 (GLP-1) reportedly exerts vasodilatory actions, and inhibitors of dipeptidyl peptidase-4 (DPP-4), an enzyme-degrading GLP-1, are widely used to treat T2DM. We therefore hypothesized that DPP-4 inhibitors (DPP-4Is) improve endothelial function ...

Dipeptidyl peptidase-IV (DPP-IV) merupakan salah satu target dalam pengobatan diabetes tipe-2. Beberapa obat golongan gliptin yang tersedia secara komersial seperti sitagliptin, anagliptin, linagliptin, saxagliptin, dan alogliptin khusus digunakan sebagai inhibitor DPP-IV untuk pasien diabetes. Saat ini, penggunaan peptida pada protein susu kambing mengobati telah dilaporkan berbagai percobaan ...

Abstract Polymer semiconductors are promising materials for stretchable, wearable, and implantable devices due to their intrinsic flexibility, facile functionalization, solution processability at low temperatures. However, the crystalline domain of conjugated structure high charge carrier mobility in semiconducting polymers exhibits lower stretchability than that semi‐crystalline or amorphous d...

JCB • VOLUME 176 • NUMBER 1 • 2007 4 Dying cel ls make a jo int A leg that doesn’t bend is not much use. To make space for joints in the fruit fl y limb, a thin band of cells are carved out by apoptosis, according to a new study by Cristina Manjón, Ernesto Sánchez-Herrero, and Magali Suzanne (Autonomous University of Madrid, Spain). The team shows that a sharp switch in morphogen signaling dete...