In general, computer aided design support systems have got an approach of traditional artificial intelligence, which statistically analyzes data such as the behavior of designer, to extract formal design behavior. This approach, however, can neither deal with continuous change of fashion nor reflect personal taste well, as it just depends on large amount of collected data. To overcome this sort...

The American College of Medical Informatics is an honorary society established to recognize those who have made sustained contributions to the field. Its highest award, for lifetime achievement and contributions to the discipline now known more inclusively as biomedical informatics, is the Morris F Collen Award. Dr. Collen’s own efforts as a pioneer in the field stand as the embodiment of creat...

BACKGROUND Drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms (DIHS/DRESS) and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) represent contrasting poles of severe drug eruptions, and sequential reactivations of several herpesviruses have exclusively been demonstrated in the former. No previous studies, however, were extended beyond the acu...

BACKGROUND Severe cutaneous adverse reactions to drugs (SCARs) include acute generalized exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS) and epidermal necrolysis (Stevens-Johnson syndrome-toxic epidermal necrolysis [SJS-TEN]). Because of the varied initial presentation of such adverse drug reactions, diagnosis may be difficult and suggests overlap ...

PATIENT Female, 24 FINAL DIAGNOSIS: DRESS syndrome Symptoms: Fever • rash • facial and body swelling • muscular pain • diarrhea MEDICATION Ciprofloxacin Clinical Procedure: - Specialty: Internal Medicine • Hematology. OBJECTIVE Unusual or unexpected effect of treatment. BACKGROUND Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a rare, potentially life-threatening drug re...