نتایج جستجو برای: dried blood spot test

تعداد نتایج: 1483626  

Journal: :Canadian Journal of Gastroenterology and Hepatology 2019

Journal: :Clinical chemistry 1989
T Fujimoto Y Tsuda R Tawa S Hirose

In this improved simple method for determination of aminoglycoside antibiotics in dried-blood spots on filter paper, gentamicin or netilmicin is recovered from the blood spot most effectively by incubation for 60 min in an ultrafiltration tube containing 500 microL of 0.5 mol/L Na2HPO4 buffer. The eluates from the paper are centrifuged, then transferred to an Abbott TDx cartridge for measuremen...

Journal: :Antimicrobial agents and chemotherapy 2016
A E Kip H Rosing M J X Hillebrand S Blesson B Mengesha E Diro A Hailu J H M Schellens J H Beijnen T P C Dorlo

To facilitate future pharmacokinetic studies of combination treatments against leishmaniasis in remote regions in which the disease is endemic, a simple cheap sampling method is required for miltefosine quantification. The aims of this study were to validate a liquid chromatography-tandem mass spectrometry method to quantify miltefosine in dried blood spot (DBS) samples and to validate its use ...

2016
Beyene Wondafrash Desta Hiko

BACKGROUND Infants and children living with HIV receive antiretroviral treatment often late, are exposed to opportunistic infection and quickly develop AIDS. Few hospitals are providing ART service after Dried Blood Spot (DBS)test.The objective of this study is to assess the status of infants and children linked to ART. METHODS Descriptive cross-sectional study was conducted in hospitals. Dat...

Journal: :Clinical chemistry 2013
Devin Oglesbee Charles Kroll Oleksandr Gakh Eric C Deutsch David R Lynch Ralitza Gavrilova Silvia Tortorelli Kimiyo Raymond Dimitar Gavrilov Piero Rinaldo Dietrich Matern Grazia Isaya

BACKGROUND Friedreich ataxia (FRDA) is caused by reduced frataxin (FXN) concentrations. A clinical diagnosis is typically confirmed by DNA-based assays for GAA-repeat expansions or mutations in the FXN (frataxin) gene; however, these assays are not applicable to therapeutic monitoring and population screening. To facilitate the diagnosis and monitoring of FRDA patients, we developed an immunoas...

Journal: :The Journal of Clinical Endocrinology & Metabolism 2016

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