نتایج جستجو برای: drug combinations
تعداد نتایج: 659226 فیلتر نتایج به سال:
Complex diseases like cancer are regulated by large, interconnected networks with many pathways affecting cell proliferation, invasion, and drug resistance. However, current cancer therapy predominantly relies on the reductionist approach of one gene-one disease. Combinations of drugs may overcome drug resistance by limiting mutations and induction of escape pathways, but given the enormous num...
Drug combinatorial therapy could be more effective in treating some complex diseases than single agents due to better efficacy and reduced side effects. Although some drug combinations are being used, their underlying molecular mechanisms are still poorly understood. Therefore, it is of great interest to deduce a novel drug combination by their molecular mechanisms in a robust and rigorous way....
Results: • There were no noticeable effects of the environmental conditions (choice of diluents, temperature or blue light phototherapy) on the physical or chemical compatibility of the drug mixtures. • The precipitation observed in some of the incompatible combinations has been established to be due to either a change in pH that is incompatible with the formulation or in the case of ketamine t...
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