BACKGROUND Clinical practice guidelines are widely distributed by medical associations and relied upon by physicians for the best available clinical evidence. International findings report that financial conflicts of interest (FCOI) with drug companies may influence drug recommendations and are common among guideline authors. There is no comparable study on exclusively Canadian guidelines; ther...

BACKGROUND The current direct-to-consumer advertising (DTCA) guidelines were developed with print, television, and radio media in mind, and there are no specific guidelines for online banner advertisements. OBJECTIVE This study evaluates how well Internet banner ads comply with existing Food and Drug Administration (FDA) guidelines for DTCA in other media. METHODS A content analysis was per...

The human genome sequence provided a complete molecular ‘parts list’ for researchers interested in improving human health. A key task now is to catalogue how the gene products interact with drugs and drug-like molecules. ChEMBL is a ‘chemogenomic’ database that brings together chemical, bioactivity and genomic data to aid the translation of genomic information into effective new drugs. The reso...