reye's syndrome is defined as fatty liver degeneration and acute encephalopathy following diffused abnormal mitochondrial activity. we reported a two year old girl admitted with lethargy and meningismus despite no evidence of blood sugar decrease, history of previous viral disease or drug use, complete tests showed reye syndrome as the final diagnosis. conservative protocols and treatment inclu...

Resistance to xenobiotics remains a pressing issue in parasite treatment and global agriculture. Multiple factors may affect the evolution of resistance, including interactions between life-history traits and the strength of selection imposed by different drug doses. We experimentally created replicate selection lines of free-living Caenorhabditis remanei exposed to Ivermectin at high and low d...

An estimated 70% of adult men and 60% of adult women in the United States are overweight or obese.1 Excess body fat increases the likelihood of developing hypertension, dyslipidemia, and type 2 diabetes mellitus and is an independent risk factor for cardiovascular disease.2–4 Obesity is linked to an increased risk for certain cancers, osteoarthritis, and sleep apnea.5–8 Obese people are stigmat...

An interaction between divalproex sodium and topiramate may induce hyperammonemic encephalopathy, a well-documented, but seemingly overlooked or minimized adverse drug interaction. This case report highlights a 54 year old Caucasian female who presented with sedation, mental status changes, and a history of repeated hospitalizations of similar presentation along with hyperammonemia. The patient...

OBJECTIVE This study examined the gender differences in drug-related problems and predictors of recidivism among a sample of 1444 offenders with co-morbid drug abuse and mental disorders participating in California's Proposition 36 Program. METHODS Background characteristics and problem severity in multiple key life areas were assessed at intake by using Addiction Severity Index, and drug tre...

OBJECTIVES This study was conducted to identify the prevalence of and potential risk factors for HIV-1 infection among drug users visiting drug treatment centers in Tehran, Iran. DESIGN Cross-sectional quantitative study. METHODS Between October 2003 and May 2004, drug users who visited three public drug treatment centers in Tehran were interviewed and information about their sociodemograph...

BACKGROUND People living with HIV (PLHIV) who are also marginalized by social and structural inequities often face barriers to accessing and adhering to HIV treatment and care. The Dr. Peter Centre (DPC) is a non-profit integrated care facility with a supervised injection room that serves PLHIV experiencing multiple barriers to social and health services in Vancouver, Canada. This study examine...

BACKGROUND Since 2003 Thailand has waged an aggressive "war on drugs" campaign focused on arresting and incarcerating suspected drug users and dealers. However, little is known about incarceration experiences among IDU in the wake of the recent war on drugs. Therefore, we sought to examine incarceration experiences among IDU in Bangkok, Thailand. METHODS We examined the prevalence of incarcer...

background: drug abuse is a major health problem in many countries. noticing the different patterns of drug abuse in different areas, we evaluated the epidemiology of drug abuse and related factors in fars province, southern iran. materials and methods: in a one-year cross-sectional study, from march 21st, 2009 to 2010, all subjects referring to addiction treatment clinic of shiraz university w...

An estimated 70% of adult men and 60% of adult women in the United States are overweight or obese.1 Excess body fat increases the likelihood of developing hypertension, dyslipidemia, and type 2 diabetes mellitus and is an independent risk factor for cardiovascular disease.2–4 Obesity is linked to an increased risk for certain cancers, osteoarthritis, and sleep apnea.5–8 Obese people are stigmat...