We present a clinical case of acute hepatitis confirmed by liver biopsy. A 24-year-old patient underwent pulse therapy with methylprednisolone due to the onset multiple sclerosis. The enzyme values were within normal range 15 days later. Blood tests revealed development cytolysis syndrome during an unrelated medical examination two months Obvious causes excluded, and biopsy was performed verify...

abstract        background and objective: this study was conducted to evaluate epidemiology of risk factors for hepatitis c virus (hcv) transmission, and determine the association of its genotypes with viral load and response to treatment in patients referred to the infectious disease clinic of khorramabad.         methods: the study included patients infected with hepatitis c referred to the i...

The arrival of new antiviral drugs to treat chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections has given rise to great expectations along with concerns regarding the selection of drug-resistant variants. Many lessons learnt from HIV therapeutics can be helpful for designing adequate treatment strategies against viral hepatitis, the avoidance of sequential weak monotherapies ...

Only a few case studies have been reported about antipsychotic-induced hepatitis for second generation antipsychotics. A 52-year old patient with recurrent schizoaffective psychosis was switched over from clozapine to aripiprazole monotherapy. Six weeks afterwards the otherwise asymptomatic patient presented herself with skin and scleral jaundice. Hepatic laboratory parameters and liver histolo...

Granulomatous hepatitis is not a uniform disease entity but a generic histopathologic diagnosis. The present review of aetiology and epidemiology of granulomas in the liver, shows that in the past tuberculosis and sarcoidosis were the most frequent but there remained a large percentage of "undiagnosis" cases; at the present drug-induced granulomatous hepatitis are frequently reported and "undia...

Information has been obtained from the experimental transmission of infectious hepatitis to human volunteers (1 to 7) to indicate that the icterogenic agent, which is known to be in the blood and stools of patients during active stages of the disease, is filtrable and may be transmitted to human volunteers by feeding or by parenteral inoculation of infectious material. Although the exact nature...

Phylogenetic and recombination analysis was performed on 32 complete hepatitis E virus (HEV) genomes from infected humans and pigs. For the first time, evidence for recombination between divergent HEV strains was obtained, with at least two strains being found to have discordant phylogenetic relationships consistent with the occurrence of intragenotype recombination. This finding confirms that ...

The study of pattern of acute viral hepatitis (AVH) in children revealed that hepatitis A was most common in children (59.3%) followed by NANB hepatitis (29.7 %). A dual infection with hepatitis A and hepatitis B was present in 4.4% of cases. Hepatitis A was more commonly diagnosed in younger children (54.9%) while the frequency of NANB hepatitis increased with the advancing age. Liver function...

Hepatitis C virus (HCV) infection is a significant problem among haemodialysis populations worldwide. 'Horizontal' cross-infection between patients can occur, predominately through direct environmental transmission of the virus. Current guidelines thus recommend universal barrier precautions, however they do not suggest using dedicated machines for HCV-positive patients to prevent the 'sequenti...

OBJECTIVE To describe the impact of a hepatitis A vaccination program for Indigenous children in north Queensland. DESIGN Enhanced surveillance of all notified cases of hepatitis A in north Queensland from 1996 to 2003. SETTING North Queensland; population, 596 500 people, including about 6900 Indigenous children aged under five years. INTERVENTIONS Hepatitis A vaccine was provided to Ind...