It is suggested to screen for bone metastases with bone scans and monitor for lymph node and visceral metastases/progression with imaging of the abdomen and chest. Patients with a rapid PSA doubling time (PSADT) (<8 months) are at risk for developing earlier metastases. Imaging in these patients should be performed every 3 to 6 months. Patients with slower PSA DT (>12 months) should be screened...

Combinatorial methods have emerged as valuable tools for the discovery of proteins, nucleic acids, and small molecules with novel structures and properties. While combinatorial methods can generate de novo proteins with native-like properties, finding such proteins in libraries containing an abundance of non-native structures has proved difficult and tedious. To overcome these difficulties, we ...

Dosimetric differences were investigated among single and dual arc RapidArc and fixed-field intensity-modulated radiotherapy (f-IMRT) treatment plans for whole pelvic irradiation of lymph nodes. A total of 12 patients who had undergone radical surgery for cervical cancer and who had demonstrated multiple pelvic lymph node metastases were treated with radiotherapy. For all 12 cases, 7-field IMRT...

eccrine gland metabolism. It is well known that lactate concentration increases during physical exercise, being a useful parameter to monitor wellness, physical fitness and the effects of exercise . Detection in sweat offers a less invasive, and dynamic way of measuring lactate concentration, particularly during exercise. Current methods of detection of lactate include fibre optics, conducting ...

In developing countries, diligent efforts have been devised to screen and monitor the patients closely and have helped preventing morbidity and mortality due to iron overload. However, infection-related deaths in developing and developed countries still occur [2]. Invasive fungal infections are the major cause of infections in patients with thalassemias. This high mortality rate stems, in part,...

3-Hydroxy-3-methylglutaric aciduria was detected in a newborn. The progress of the dietary therapy for the disorder was monitored by dual-column "high-performance" liquid chromatography with a computer-controlled photodiode array spectrophotometric detector. This procedure is a quick way to detect and monitor the progress of 3-hydroxy-3-methylglutaric aciduria.

Scanning electrochemical cell microscopy (SECCM) is demonstrated as a new approach for the construction of extended multi-dimensional conducting polymer (polyaniline) nanostructures, making use of a mobile dual-channel theta pipette cell to control and monitor the location, rate and extent of electropolymerisation.

Firefly luciferases are widely used as bioluminescent reporter genes for bioimaging and biosensors. Aiming at simultaneous analyses of different gene expression and cellular events, luciferases and GFPs that exhibit distinct bioluminescence and fluorescence colors have been coupled with each promoter, making dual and multicolor reporter systems. Despite their wide use, firefly luciferase biolum...

Strong ionosphere storms are a potential threat for the Local Area Augmentation System (LAAS). During these storms, very large spatial gradients of ionosphere delays might cause significant errors in user position estimation. Therefore, LAAS needs to continuously monitor ionosphere behavior in order to ensure integrity against the ionosphere anomalies. This paper introduces a new ionosphere mon...