The present study aimed to determine whether the expression of microRNA (miR)-10b was correlated with the molecular subtypes of early invasive ductal carcinoma of the breast. In situ hybridization was used to detect the expression of miR-10b in 193 patients diagnosed with early invasive ductal carcinoma. Immunohistochemistry was performed to evaluate the expression of estrogen receptor (ER)-α, ...

BACKGROUND There has been growing interest in the overdiagnosis of breast cancer as a result of mammography screening. We report incidence rates in British Columbia before and after the initiation of population screening and provide estimates of overdiagnosis. METHODS We obtained the numbers of breast cancer diagnoses from the BC Cancer Registry and screening histories from the Screening Mamm...

INTRODUCTION The utility of FDG PET/CT for the detection and evaluation of invasive ductal carcinoma has been widely reported, but a few studies have assessed the utility of FDG PET/CT to detect malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. PURPOSE To compare the diagnostic performance of visual estimation with the semi-quantitative scores of FDG PET/CT f...

OBJECTIVE To determine the association between thymidine phosphorylase (TP) and angiogenesis, and other conventional prognostic markers. We also evaluated interobserver and intraobserver reliability for TP expression in ductal carcinoma, to achieve a more consistent results. METHODS Our study included all cases diagnosed in Adnan Menderes University Medical Faculty Hospital, Aydin, Turkey as ...

We have examined ten human subjects with a previously developed instrument for near-infrared diffuse spectral imaging of the female breast. The instrument is based on a tandem, planar scan of two collinear optical fibers (one for illumination and one for collection) to image a gently compressed breast in a transmission geometry. The optical data collection features a spatial sampling of 25 poin...

Breast cancer tissues have been analyzed to determine the feasibility of the chemical changes taking place in the biological tissue, which can be identified and categorized into various grades. FTIR spectroscopy can be used for qualitative analysis of cancerous breast tissues because of its sensitivity to the changes in the biomolecules in the tissues. IR spectra was taken for a total number of...

An adenoid cystic carcinoma of the breast in a 78 year old woman was analysed immunohistologically for the production of type IV collagen, the expression of vimentin, epithelial membrane antigen (EMA) and steroid receptors, and the proliferative activity of the tumour cells. The data were compared with those obtained in eight adenoid cystic carcinomas of salivary glands and in ductal carcinomas...

Objective : To determine the relations between human papilloma viruses type 16 and type 18 infection and the expression of p53 protein in invasive ductal carcinoma. Methods : We detected the expression of HPV 16/18 DNA and p53 protein in invasive ductal carcinoma in 45 cases, breast fibroadenoma in 20 cases and normal breast tissues in 20 cases. HPV detection was performed on paraffin sections ...

Repeated pancreatectomy for pancreatic carcinoma is extremely rare. We report two such patients who underwent pancreatectomy for carcinoma developing in the pancreatic remnant after pylorus-preserving pancreatoduodenectomy (PpPD) for invasive pancreatic ductal carcinoma. One patient underwent PpPD for invasive pancreatic ductal carcinoma and received adjuvant chemotherapy. Follow-up computed to...

The aim of this study was to investigate the value of quantitative 3-Tesla (3T) magnetic resonance (MR) assessment in the diagnosis of breast lesions. A total of 44 patients with breast lesions were selected. All the patients underwent MR plain scanning and T1 dynamic contrast-enhanced imaging. The vascular function parameters of the lesions, namely volume transfer constant (Ktrans), rate const...