Mouse (m) and human embryonic stem cell-derived cardiomyocytes (hESC-CMs) are known to exhibit immature Ca(2+) dynamics such as small whole-cell peak amplitude and slower kinetics relative to those of adult. In this study, we examined the maturity and efficiency of Ca(2+)-induced Ca(2+) release in m and hESC-CMs, the presence of transverse (t) tubules and its effects on the regional Ca(2+) dyna...

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The Model-Driven Engineering paradigm has become increasingly popular due to its advocation of using models as first-class citizens in the software development process, while artifacts such as documentation and source-code can be produced from those models by using automated transformations. On the other hand, we are currently witnessing the rise in popularity of a particular kind of web-applic...

The effect of external as well as internal bremsstrahlung radiation in H ! ZZ ! 4e channel is studied in full detector simulation. A method is proposed for external and internal bremsstrahlung recovery, allowing us to use 95% of electrons within j E=pgen 1 j 0.2. It is shown that traditional E=p and isolation cuts can be implemented with 90% efficiency, but that precise mass reconstruction is a...

Suspensions of fat cells were prepared from rat epididymal adipose tissue by digestion of the tissue with crude bacterial collagenase. One portion of each suspension was exposed to p-chloromercuribenzenesulfonic acid (CMS), washed, and then incubated in Krebs-Ringer-bicarbonate buffer. A second portion, the control, was not exposed to CMS, but it was otherwise treated identically. Acceleration ...

BackgroundAccumulating research substantiated that tumor-associated macrophages (TAMs) have a significant impact on the tumorigenesis, progression, and distant metastasis, representing novel target for various cancers. However, underlying dynamic changes interactions between TAMs tumor cells remain largely elusive in colorectal cancer (CRC).MethodsWe depicted of using sing-cell RNA-seq data ext...

As IS researchers, we continuously look for relevance of IT artifacts and its influences on various spheres of business. The advent of content management systems (CMS) brings out possibilities of research in the area. Organizations are increasingly using CMS to manage diverse range of content. Academic research on organizational impact of CMS is very limited. Hence, this paper explores the how ...

This document describes an additional content type for the Cryptographic Message Syntax (CMS) [CMS]. The authenticatedenveloped-data content type is intended for use with authenticated encryption modes, where an arbitrary content is both authenticated and encrypted. Also, some associated data in the form of authenticated attributes can also be authenticated. All of the various key management te...

congenital myasthenic syndromes (cms) are a group of diseases caused by genetic defects affecting neuromuscular transmission and are heterogeneous in inheritance and pathophysiology. these are classified as: 1. presynaptic defects: including choline acetyl transferase deficiency, paucity of synaptic vesicles, lambert-eaton like cms 2. synaptic defect: endplate ach esterase deficiency 3. postsyn...

We present a method to enhance the accuracy of platform-based, high-frequency (HF) direction-finding (DF) systems using dynamic mode selection. To improve bandwidth and efficiency, metallic platform supporting DF array is used as primary radiator by employing electrically small antennas excite linearly independent combinations its characteristic modes (CMs). However, radiation characteristics t...