BACKGROUND/AIMS Temperament and mood swings are promising indicators for the characterization of mood spectrum vulnerability. The aim of this study was to investigate the relationship between affective temperament and mood swings in bipolar disorder. We explored these clinical features retrospectively. METHODS Patients who met the criteria for bipolar I disorder were enrolled in the study. Ex...

OBJECTIVE Researchers disagree as to whether irritability is a diagnostic indicator for pediatric mania in bipolar disorder. The authors compared the behavioral and psychophysiological correlates of irritability among children with severe mood dysregulation (i.e., nonepisodic irritability and hyperarousal without episodes of euphoric mood) and narrow-phenotype bipolar disorder (i.e., a history ...

Objectives and Methods. This was an observational study of the efficacy of short-term psychodynamic psychotherapy (STPP) in a sample of 35 (30 women and 5 men) patients with moderate-to-severe "male depression" (Gotland Scale for Male Depression (GSMD) ≥ 13) comorbid with unipolar mood disorder (dysthymia and major depression) or anxiety disorder. Outcome measures were GSMD and BHS (Beck Hopele...

Major depressive disorder and bipolar disorder share symptoms that may reflect core mood disorder features. This has led to the pursuit of intermediate phenotypes and a dimensional approach to understand neurobiological disruptions in mood disorders. Executive dysfunction, including cognitive control, may represent a promising intermediate phenotype across major depressive disorder and bipolar ...

Background: Bipolar mood disorder type 1 is one of the most serious psychiatric disorders. We aimed to assess the efficacy of a short-term family–focused treatment for patients with bipolar mood disorder type 1 in a one-year follow-up period. Methods: Sixty patients with bipolar mood disorder and acute mania episodes who referred to Ibn-e-Sina Psychiatric Hospital in Mashhad were recruited. Hal...

results analysis showed that there were no significant differences between the groups at baseline (p < 0.05). comparison of the results between the two groups before the two-step test showed that anger and vitality scales between the two groups have no significant differences, but on the other scales (depression, dizziness, fatigue and tension), differences between pre and post-test groups were...

Neurological status of chronic depressive states have not been resolved as yet. Recent classificatory systems ICD-X and DSM-III-R have included chronic depression under affective disorders and have done away with the category of neurotic depression. The present study was undertaken with the aims of (a) to study clinical variables associated with major subtypes of chronic depression (chronic maj...

OBJECTIVE To examine longitudinally the effects of Assertive Community Treatment (ACT) on Global Assessment of Functioning (GAF) scores in Edmonton, Alberta. METHODS We acquired GAF scores for all clients at initial registration in the ACT program and at subsequent 18- and 36-month time points while in ACT. We analyzed both the entire ACT cohort and separate diagnostic groups. RESULTS We ob...