friedreich’s ataxia (frda) is a rare autosomal recessive spinocerebellar ataxia which in the majority of cases is associated with a gaa-trinucleotide repeat expansion in the first intron of frataxin gene located on chromosome 9. the clinical features include progressive gait and limb ataxia, cerebellar dysarthria, neuropathy, optic atrophy, and loss of vibration and proprioception. ataxia with ...

radiation induced sarcoma is a rare but recognized complication of radiotherapy and is associated with poor prognosis, frequently occurs 5 years after completion of treatment. we report radiation-induced sarcoma in a 42 years old male, involving the left parietooccipital scalp region following treatment of brain tumor with craniotomy and post-operative radiation with 60co machine. diagnosis of ...

adult periodontitis is a complex multifactorial disease whose etiology is not well defined. the pro-inflammatory and bone resorption properties of interleukine-1α (il-1α) strongly suggest a role for this cytokine in the pathogenesis of periodontal disease. eighty iranian adult patients with periodontitis and 80 iranian controls were investigated in this study. in this study we report that the f...

Resolution of inflammation is an active temporally orchestrated process demonstrated by the biosynthesis of novel proresolving mediators. Dysregulation of resolution pathways may underlie prevalent human inflammatory diseases such as cardiovascular diseases and periodontitis. Localized Aggressive Periodontitis (LAP) is an early onset, rapidly progressing form of inflammatory periodontal disease...

Tooth autotransplantation, that is the surgical movement of a tooth from its original location to another site within same person, an alternative dental implantation because it can save time, provide faster healing and function, has esthetic advantages. A unique sensory system be maintained, procedure promotes proper periodontal environment. We report on case external fistula with apical period...

priapism is a prolonged and usually painful erection which is not associated withthe sexual desire. ït is an uncommon urologic emergency with variety ofknown etiologies such as the use of psychotropic medications. priapism underconcurrent treatment with chlorpromazine and risperidone has notbeen reported so far. herein, a psychotic patient whodeveloped priapism during chlorpromazine and risperi...

zellweger syndrome (zs) is a peroxisomal disorder with a multiple congenital anomalies, characterized by stereotypical facies, profound hypotonia, organ involvement including cerebral, retinal, hepatic, and renal. herein, a 3-month-old female with zs is presented who was referred because of increased liver enzymes (subclinical hepatitis), which was detected in work-up of her neck cyst, severe h...

BACKGROUND Periodontitis was shown to have an impact on glucose levels in prediabetic and diabetic rats. The Zucker fatty rat (ZFR) is a well-characterized model of prediabetes presenting with impaired glucose tolerance, hyperinsulinemia, dyslipidemia, and moderate hypertension. The aim of the present study was to investigate whether periodontitis influences kidney changes in ZFRs. METHODS Ma...