Background. Ongoing surveillance of antimicrobial sensitivity patterns of bacteria isolated in bloodstream infections guides empiric antibiotic therapy in neonatal sepsis. Methods. Sensitivity profiles of neonatal bacterial bloodstream infections in a tertiary hospital were reviewed between 01/06/2009 and 30/06/2010 . Results. There were 246 episodes of bloodstream infection in 181 individuals-...

Vitamin D is a fat-soluble vitamin that is important for calcium metabolism and plays an important role in the immune functions. The aim of this study was to measure neonatal and maternal 25-OH vitamin D serum levels in neonates with early onset sepsis. The study included fifty neonates with early onset sepsis (25 full-term and 25 preterm infants) and thirty age and sex matched healthy neonates...

Sepsis is a highly lethal syndrome with heterogeneous clinical manifestation that can be hard to identify and treat. Early diagnosis appropriate treatment are critical reduce mortality promote survival in suspected cases improve the outcomes. Several screening prediction systems have been proposed for evaluating early detection of patient deterioration, but efficacy still limited at individual ...

Background Neonatal sepsis contributes substantially to neonatal morbidity and mortality, and is an ongoing major global public health challenge. We aimed to evaluate the effects of enteral feeding supplementation of low dose lactulose on the incidence of late onset sep...

Correspondence When to do a lumbar puncture in a neonate Sir, We enjoyed Dr Halliday's annotation on neonatal lumbar puncture but felt that his discussion of the role of lumbar puncture in suspected sepsis left an unfortunate question mark hanging over this procedure.' It is important we feel to distinguish between early onset and late onset sepsis. In early onset sepsis the usual route of infe...

PURPOSE To evaluate the diagnostic performance of maternal inflammatory marker: C-reactive protein (CRP) in predicting early onset neonatal sepsis (that occurring within 72 hours after birth). MATERIALS AND METHODS 126 low birth weight newborns (gestation 32±3.2 wk, birth weight 1887±623 g) and their mothers were included. Neonates were divided into sepsis group (n=51) including both proven (...

statement of problem: patients affected with “early onset periodontitis” (eop), are not similar regarding their neutrophil deficiency and researches have yielded contradictory results in this field. purpose: the purpose of this study was to evaluate different aspects of neutrophils’ activities in peripheral blood of such patients, especially those affected with prepubertal periodontitis and juv...

Group B streptococcus (GBS) is a commonly recognized cause of sepsis and meningitis in neonatal and young infants. Invasive GBS infection is classified into early onset GBS disease (EOD, day 0-6), late onset GBS disease (LOD, day 7-89) and ultra late onset GBS disease (ULOD, after 3 months of age). ULOD is uncommon and recurrence is especially rare. We present the first recurrent case of ULOD G...

BACKGROUND Group B streptococcus (GBS) infection remains a major cause of neonatal morbidity and mortality, and GBS III is the predominant strain in early-onset GBS neonatal sepsis. To avoid both over- and undertreatment of infants with nonspecific signs of infection, early diagnostic tools are warranted. The aim of this study was to identify biomarkers with high sensitivity and specificity in ...