Prevention of infection, as well as bone covering and healing, is paramount in the management of limb injury with associated muscle injury. Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle with resultant functional impairment. No standardized evaluation protocol exists for the characterization and quantification of VML. Clinical photographs and video recordings,...

One method of assessing the potential efficacy of various clinical treatments is the use of computational modelling. Previous modelling studies have indicated that ideal muscle activation patterns could produce a better immediate corrective pattern than bracing . This would suggest that there is great potential in electrical stimulation, but compared with bracing, and with a general lack of cli...

in recent years, seismic evaluation and vulnerability of the existing buildings, that have been designed based on an earlier seismic design code or designed without seismic design criteria, has been very important. in this paper, the seismic evaluation and vulnerability of concrete buildings, using an old 5- story building with shear walls as an example has been discussed. for this building, fi...

The heart has two major modalities of hypertrophy in response to hemodynamic loads: concentric and eccentric hypertrophy caused by pressure and volume overload (VO), respectively. However, the molecular mechanism of eccentric hypertrophy remains poorly understood. Here we demonstrate that the Akt-mammalian target of rapamycin (mTOR) axis is a pivotal regulator of eccentric hypertrophy during VO...

Drilling is the most frequently employed operation of secondary machining for fiber-reinforced materials owing to the need for structure joining. Delamination is one of the serious concerns during drilling. Practical experience shows that an eccentric twist drill or an eccentric candle stick drill can degrade the quality of the fiber reinforced material. Comprehensive delamination models for th...

Over the last 20 years a number of studies have been published using progressive eccentric exercise protocols on motorized ergometers or similar devices that allow for controlled application of eccentric loads. Exercise protocols ramp eccentric loads over an initial 3 weeks period in order to prevent muscle damage and delayed onset muscle soreness. Final training loads reach 400-500 W in rehabi...

in this paper we present explicit formulas for the eccentric connectivity index of three classesof chain hexagonal cacti. further, it is shown that the extremal chain hexagonal cacti withrespect to the eccentric connectivity index belong to one of the considered types. some openproblems and possible directions of further research are mentioned in the concluding section.