Previous examination of the effect of TCF-4 on transcription of the human immunodeficiency virus type 1 (HIV-1) promoter in human astrocytic cells found that TCF-4 affects the HIV-1 promoter through the GC-rich domain (nt -80 to nt -68). Here, the physical interaction and a functional consequence of TCF4-Sp1 contact were characterized. It was shown that expression of TCF-4 in U-87 MG (human ast...

صلاخلا ــ ة : مت ةقرولا هذه يف ءاشنإ يف هدعاسملل مدقتم ماظن بناوج ذيفنتو ميمصت ضرع قتو و مي ءادأ حيحصت تارفش لأا ءاطخ ةليلق لا ةناتم ، ةينبم ىلع ءوفاكتلا رايتخا . موقي امه نيتيسيئر نيتفيظوب ةساردلا هذه يف مدقتملا ماظنلا : 1 ادأ باسحل ةيزاوتملا هاآاحملا ء تارفش حيحصت لأا ءاطخ ةليلق نمزب ةفاثكلا ادج ريصق ةنراقم ةمظنأب ةاآاحملا ةدوجوملا . 2 ةليلق ءاطخلأا حيحصت تارفشو فعضلا قطانم صحف نع ة...

After injection, heroin is rapidly metabolized to 6-monoacetylmorphine (6-MAM) and further to morphine. As morphine has been shown to increase striatal dopamine, whereas 6-MAM has not been studied in this respect, we gave i.v. injections of 3 μmol 6-MAM, morphine or heroin to rats. Opioids were measured in blood, and dopamine and opioids in microdialysate from brain striatal extracellular fluid...

The relationships between the intensification rate (IR) and size configuration of tropical cyclones (TCs) are investigated. Theoretically, intensity, configuration, relative vorticity TCs intrinsically linked. TC fullness (TCF) is used to quantify can be expressed as product critical (TCF0) ratio (Rf). TCF0 represents fundamental constraint on shared by at a given intensity lower limit fullness...

Study on electrodes, which are inserted into electro-conjugate fluid (ECF) and generate ECF jet, is still in progress. A sort of so-called triangular-prism-slit (TPS) electrode structure was proposed and it is often thought as a promising candidate for future ECF effect applications thanks to its relatively high performance and easy fabrication. Besides considering power density characteristic ...

In a product market with price-sensitive demand, we examine supply chain consisting of one manufacturer and capital-constrained retailer. The retailer may purchase by borrowing securing confirmed warehouse financing (CWF) from competitive bank or the manufacturer's trade credit (TCF), provided that it is also to latter's benefit extend TCF. We obtain optimal pricing decision in two modes under ...

Since the empirical characteristic function (ECF) is the Fourier transform of the empirical distribution function, it retains all the information in the sample but can overcome difficulties arising from the likelihood. This paper discusses an estimation method via the ECF for strictly stationary processes. Under some regularity conditions, the resulting estimators are shown to be consistent and...

Changes in extracellular fluid (ECF) volume of Carcinus maenas (L.) were studied in vivo during acclimation to low and high environmental salinities. Initial investigations showed that there was a rapid equilibration into this compartment of the ECF markers used ([H]inulin and pKJjhydroxymethyl inulin). Earlier reports of a relatively slow marker distribution, indicated from clearance curves, c...

Energy coupling factor (ECF) transporters are responsible for the uptake of essential scarce nutrients in prokaryotes. This ATP-binding cassette transporter family comprises two subgroups that share a common architecture forming a tripartite membrane protein complex consisting of a translocation component and ATP hydrolyzing module and a substrate-capture (S) component. Here, we present the cry...