background: sickle-cell disease (scd) is an inherited hemoglobin childhood disorder, frequently complicated by pulmonary hypertension and cardiac involvement. cardiovascular events and complications are the leading cause of mortality and morbidity in patients with scd. tissue doppler imaging and the myocardial performance index (tei index), are simple indices for the assessment of the cardiac f...

Abstract Background and Aims In patients with diabetes mellitus diabetic nephropathy, a high incidence of left ventricular diastolic dysfunction has been reported by various studies. The objective this study was to the real world evaluation impact sodium glucose cotransporter type 2 (SGLT2) inhibitors on (LV) function (T2DM) nephropathy heart failure (HF). Method We studied Diabetes Mellitus 2,...

INTRODUCTION Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases are responsible for the generation of reactive oxygen species, producing vascular and myocardial dysfunction in diabetes mellitus. However, the potential benefits of the NADPH oxidase inhibitor, apocynin, on left ventricular (LV) remodeling remain unknown. RESULTS In the diabetic group, interventricular septal thickness...

Abstract Background/Introduction Patients with type 2 diabetes mellitus (T2DM) and ischemic stroke present impaired markers of vascular endothelial function. Glucagon-like peptide-1 receptor agonists (GLP-1) sodium-glucose contrasporter-2 inhibitors (SGLT-2) are novel antidiabetic agents reducing the risk cardiovascular complications. Purpose The aim study is to investigate effect treatment GLP...

BACKGROUND: The left ventricular global function index (LVGFI), determined using transthoracic echocardiography, is a simple clinical marker of dysfunction and has superior prognostic value to the standard ejection fraction-based assessment cardiac pump function. methodology for calculating this was proposed in 2019. Currently, factors that influence state functions are not examined.
 AIM:...

strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range. Impact of myocardial structure and function postinfarction on diastolic strain measurements: Implications for assessment of myocardial viability.gression of left ventricular diastolic dysfunction and risk of heart failure. Normal ranges of left ven-tricular strain: a meta-analysis. Inter-study r...

OBJECTIVE To determine the frequency of diabetic cardiomyopathy among patients with type-2 diabetes presenting with overt heart failure. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY Department of Cardiology, Mayo Hospital, Lahore, from April 2008 to July 2009. METHODOLOGY One hundred patients with type-2 diabetes mellitus having symptoms and signs of heart failure were enrolled. ...

BACKGROUND In comparison to the well established changes in compliance that occur at the large vessel level in diabetes, much less is known about the changes in compliance of the cardiovascular system at the end-organ level. The aim of this study was therefore to examine whether there was a correlation between resistance of the intrarenal arteries of the kidney and compliance of the left ventri...

conclusions there is a significant increased incidence of mortality, prolonged hospitalization, and rehospitalization in symptomatic patients with severe tr. therefore, we recommend more aggressive approach toward tv repair or replacement in these patients regardless of pap and systolic function. results heart failure (50%) was the most cause of death. mean years of survival from diagnosis of s...