Unsealed radioactive sources such as 131I and 99mTc are used in Nuclear Medicine Centers, to diagnose and treat patients, pose significant risks of internal exposure to the occupational workers. 131I is highly volatile and radiotoxic, which may pose an occupational radiological hazard, especially in places where significant activities are routinely handled. In such situations, worker handling u...

PURPOSE In Korean society, extra-large hospitals are congested with the majority of patients. Because of the congestions, the urgent patients need to wait anywhere from as short as a month to around three months. These concentrations of the patients on the extra-large hospitals causes not only the economic problem in terms of loss of opportunity cost and resources of other medium and large hosp...

The strong ion approach provides a quantitative physicochemical method for describing the mechanism for an acid-base disturbance. The approach requires species-specific values for the total concentration of plasma nonvolatile buffers (A(tot)) and the effective dissociation constant for plasma nonvolatile buffers (K(a)), but these values have not been determined for human plasma. Accordingly, th...

INTRODUCTION The use of ultrasound in regional anesthesia allows reducing the dose of local anesthetic used for peripheral nerve block. The present study was performed to determine the minimum effective concentration (MEC90) of bupivacaine for axillary brachial plexus block (ABPB). METHODS Patients undergoing hand surgery were recruited. To estimate the MEC90, a sequential up-down biased coin...

Lys120 in the DNA-binding domain (DBD) of p53 becomes acetylated in response to DNA damage. But, the role and effects of acetylation are obscure. We prepared p53 specifically acetylated at Lys120, AcK120p53, by in vivo incorporation of acetylated lysine to study biophysical and structural consequences of acetylation that may shed light on its biological role. Acetylation had no affect on the ov...

The ribavirin concentration in hamster brains was measured by a high-performance liquid chromatography (HPLC) system and a bioassay system. When ribavirin was administered intracranially at a dosage of 10 mg/kg of body weight per day for 10 days, a dosage which results in 100% survival of hamsters infected with subacute sclerosing panencephalitis (SSPE) virus and which inhibits the replication ...

BACKGROUND The fraction of inspired oxygen (F(IO(2))) is quoted for different oxygen delivery systems, but variations in inspiratory flow and tidal volume make precise measurement difficult. We developed a reliable method of measuring the effective F(IO(2)) in patients receiving supplemental oxygen. METHODS Ten subjects with chronic hypoxemia breathed through a mouthpiece with a sampling prob...

Nutrient concentration profiles are affected by the mass transport outside the biofilm, inside the biofilm, and by the structure of the biofilm. To understand the distribution of biofilm activity, it is necessary to correlate the local nutrient concentration, local mass transport in the biofilm and the biofilm structure. The correlations among surface averaged dissolved oxygen concentration, su...

it was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (ap). it seems that some other types of mechanisms must be involved in ap propagation. in this article, we...

Background: There is a rapid increase worldwide in the consumption of mineral waters which may contain different level of radioactive elements, especially 226Ra, in addition to varying amounts of beneficial salts. Therefore, a comprehensive study was planned and carried out in order to determine concentration of 226Ra natural radionuclide in bottled mineral waters that commercially available in...