Accurate liquid flow control is important in most chemical analyses. In this work, the measurement of liquid flow in microliters per minute was performed, and feedback control of the flow rate was examined. The flow sensor was arranged on a channel made in a polydimethylsiloxane (PDMS) block. The center of the channel was cooled by a miniature Peltier device, and the change in temperature balan...

To quantify the flow of small uncharged molecules into and across nanopores, one often uses ion currents. The respective ion-current fluctuations caused by the presence of the analyte make it possible to draw some conclusions about the direction and magnitude of the analyte flow. However, often this flow appears to be asymmetric with respect to the applied voltage. As a possible reason for this...

Microfluidics, an enabling and emerging technology in cancer metastasis research, has yet to be applied in the analysis of individual cells taken directly from patient carcinomas. Accordingly, we have developed an integrated microfluidic methodology to label, dissociate, transport and detect patient-derived tumour cells. Following on-chip cold perfusion of tissue with antibody and enzymes, fluo...

A new process for the manufacture of microfluidic devices based on deposition of laser-printing toner on glass substrates is described. It is an alternative method to the toner on polyester film (toner-polyester) one, previously introduced. Commercial laser printers cannot print directly on glass, thus the toner must first be printed on a special paper and then transferred by heating under pres...

We developed a numerical code which allows fast and accurate simulation of isotachophoresis (ITP). The multi-species code accounts for equilibrium chemistry, non-uniform electroosmotic flow, and dispersion. Our modeling efforts for the latter are also presented. The goal of our work is to create an efficient, accurate, validated, and uniquely-capable electrophoresis simulation code available fo...

Department of Management Information System, Far East College 49, Chung-Hua Road,,Hsin-Shih, 744, Taiwan. e-mail: [email protected] Department of Management Information System, Far East College 49, Chung-Hua Road,,Hsin-Shih, 744, Taiwan. e-mail: [email protected] Department of Engineering and System Science, National Tsing-Hua University 101, Section 2 Kuang Fu Road, Hsinchu, 300, Taiwan ...

Mixed polymer brush-grafted nanochannels—where two distinct species of polymers are alternately grafted on the inner surface of nanochannels—are an interesting class of nanostructured hybrid materials. By using a coarse-grained molecular dynamics simulation method, we are able to simulate the electrokinetic transport dynamics of the fluid in such nanochannels as well as the conformational behav...