Routine examinations with an electroreiinogram (ERG) were performed on a large number of patients. The results are discussed in those areas where the ERG aided in diagnosis, contributed to the understanding of a disease, or assisted in following the course of a disease. The electro-oculogram (EOG) as an adjunct to the ERG is also discussed. Mention is made of the few diseases which may be detec...

Purpose. To compare the photopic negative response (PhNR) of the full-field electroretinogram (ERG) to the PhNR of the focal ERGs in detecting glaucoma. Methods. One hundred and three eyes with glaucoma and 42 normal eyes were studied. Full-field ERGs were elicited by red stimuli on a blue background. The focal ERGs were elicited by a 15° white stimulus spot centered on the macula, the superote...

The multifocal m-sequence technique is a versatile set of tools for visual electrophysiology designed to provide access to the complex dynamic interplay of converging signals in the central nervous system. Here, a number of uses for the technique are demonstrated, with examples from human electroretinography. A simple relationship between the binary kernels extracted from a single experiment pe...

PURPOSE To determine whether measurements of the a-wave latency of the electroretinogram (ERG) can be made as reliably as that of the implicit time (IT) in rats. In addition, to determine the relationship between the potential level selected for the latency and the baseline potential level. METHODS ERGs, elicited by different stimulus intensities, were recorded from Long-Evans rats. The a-wav...

.raditional studies of the animal and human electroretinogram (ERG) indicate that the stimulus intensity necessary to evoke a minimal ERG from the dark adapted retina is well above the absolute threshold of vision; these studies also show that the ERG response at threshold consists of the b-wave only, and the a-wave appears at suprathreshold intensities. Recent work on the toad, rat, cat, monke...

PURPOSE To compare electroretinogram (ERG) characteristics in patients with retinitis pigmentosa (RP) and normal subjects using frequency domain analysis. METHODS Five basic ERG recordings were performed in normal subjects and patients with a clinical diagnosis of RP according to the ISCEV (International Society of Clinical Electrophysiology of Vision) protocol. Frequency domain analysis was ...

A gold foil ERG electrode is described. The device is inexpensive and simple to fabricate. Since it is hooked over the lower lid and makes minimal touch contact with the inferior limbal area, it can be used in circumstances which require prolonged testing of retinal function or in eyes with corneal pathology. Because the optics of the eye are not compromised, it is possible, with the use of app...

PURPOSE Photophobia is a debilitating clinical condition that disrupts the ability to use vision for everyday tasks in bright lighting conditions. The goal of the study is to develop a methodology to study the neural basis of photophobia and the contribution of the melanopic pathway to its etiology with differential chromatic responses by means of standard electroencephalographic recording equi...

PURPOSE To investigate the effect of simultaneously performed fluorescein angiography (FA) on full-field electroretinography (ffERG) parameters. METHOD Scotopic and photopic ffERG were performed immediately and 60 minutes after conventional FA in patients with retinal photoreceptor disorders; a-and b-wave amplitudes were compared between recordings obtained at the two time intervals in each p...

Electroretinography (ERG) is an established diagnostic technique in clinical ophthalmology and provides objective information about retinal function. This technique is also applied in basic research, where animal models of hereditary retinopathies have significantly contributed to our understanding of the composition of ERG responses in general and how retinal degenerative pathologies alter ret...