Achievement of a safe outcome for an extensive mass with hypervascularity in the extremities requires a surgical team skilled in musculoskeletal oncology. We report debulking surgery for a huge mass of elephantiasis neuromatosa in the right leg of a 56-year old man using the novel Ligasure® vessel sealing system.

Pretibial myxedema (PTM) is usually a late manifestation of Graves' disease and is relatively rare. The elephantiasis nostras variant comprises less than one percent of patient with pretibial myxedema. We report two cases of elephantiasic PTM and review the literature regarding its treatment. Therapy of the elephantiasic variant of PTM remains suboptimal at present. ( J Intern Med Taiwan 2004; ...

Lymphatic filariasis (LF) or elephantiasis is a major public health problem not only due to morbid condition but also due to social stigma, sexual incapacitation and considerable economic loss. National Health Policy 2002, aims at elimination of transmission and the prevention of disability due to LF by the year 2015, through mass drug administration (MDA) programme with annual single dose of d...