© 2002 Canadian Medical Association or its licensors T his year marks the 80th anniversary of the publication in CMAJ of the discovery of insulin by Frederick Banting and his colleagues at the University of Toronto. Some interesting historical parallels have emerged with the success of islet replacement therapy in diabetes. Up until just a few weeks ago, human islet cells were being prepared in...

BACKGROUND The transcatheter closure of the atrial septal defect (ASD) has become an alternative technique to surgical procedures. The aim of this study was to assess the immediate, short, and intermediate-term results of the transcatheter closure of the secundum ASD with the Amplatzer Septal Occluder (ASO) in adult Iranian patients. METHODS Between December 2004 and July 2008, the transcathe...

We present a case of an 82-year-old man with duodenal diverticular bleeding (DDB) who was successfully treated using transcatheter arterial embolization (TAE). Initially, endoscopy results indicated duodenal bleeding; however, the exact bleeding site could not be located. A follow-up computed tomography (CT) scan revealed contrast extravasation from a periampullary duodenal diverticulum. Repeat...

© 2000 Canadian Medical Association or its licensors Two recent deaths from artery dissection following neck manipulation by chiropractors have focused media and medical attention on the relation between sudden neck movement and cervical artery dissection. Although the first case of carotid artery dissection due to chiropractic neck manipulation was described over 50 years ago, the frequency of...

Objectives: Hepatic Schistosomiasis resulted in the morbidity from infection due to its complications of liver fibrosis. However, there are few medicines or means avai lable to contro l and t reat f ibrosis in Schistosomiasis. The aim of this study was to assess the beneficial effects of immunomodulating agents in hepatic schistosomal fibrosis. Methods: Three hundred male Swiss albino mice infe...

Methacrylate is polymer used as a bone cement in orthopedic procedures that can rarely embolize, resulting atrial perforation and pulmonary artery occlusion. Retrieval of emboli typically requires cardiopulmonary bypass deep hypothermic circulatory arrest. In this report, we describe the off-pump removal massive left methacrylate embolus using surface ultrasound localization, partial cross-clam...

objective Pulmonary embolism (PE) is considered to originate from embolization of a deep-vein thrombosis (DVT), resulting in two manifestations of one disease: venous thrombosis. However, in up to 50% of PE patients no DVT is found with ultrasonography. An explanation for this low proportion is currently lacking. Other imaging modalities may increase DVT yield in the calf or in the abdominal re...

Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are two common problems in aging men, and pose increasing concerns in health care and social burden as the population ages. In the United States, PCa accounts for over one-quarter of newly diagnosed cancers in men and ranks as the second leading cause of cancer-related death; it is estimated that one in twelve men died of cancer is du...

Search for Venous Thrombosis in Suspected Paradoxical Embolism To the Editor: Paradoxical embolism via a patent foramen ovale (PFO) has been suggested as a mechanism of otherwise unexplained, cryptogenic stroke.1 Paradoxical embolism, however, can be diagnosed only if there is evidence of a venous thrombosis coexisting with arterial embolism and right-to-left shunting via a PFO. When looking fo...

Search for Venous Thrombosis in Suspected Paradoxical Embolism To the Editor: Paradoxical embolism via a patent foramen ovale (PFO) has been suggested as a mechanism of otherwise unexplained, cryptogenic stroke.1 Paradoxical embolism, however, can be diagnosed only if there is evidence of a venous thrombosis coexisting with arterial embolism and right-to-left shunting via a PFO. When looking fo...