Although Turing's reaction-diffusion model (RD model) has been gradually accepted among biologists, application of the model is still limited. Accumulated experimental studies have shown that the morphogen gradient model can explain most patterning phenomena in embryogenesis. These experiments have been performed only in a few model animals. Therefore, it is not clear whether the discovered pri...

The bending and internalization of tissues during embryonic development is a conserved process driven by dramatic cell-shape changes. A recent study details the molecules required for mesoderm internalization in Drosophila and their unique spatial localization pattern.