Living cells are controlled by networks of interacting genes, proteins and biochemicals. Cells use the emergent collective dynamics of these networks to probe their surroundings, perform computations and generate appropriate responses. Here, we consider genetic networks, interacting sets of genes that regulate one another's expression. It is possible to infer the interaction topology of genetic...

In this paper, we investigate coordination within responder radio communications during the World Trade Center disaster. Using a network analytic approach, we identify agents who exhibit high levels of coordinative activity. Agents are further classified by whether they appear to occupy formal roles whose responsibilities include coordination of communication, and by whether the agents belong t...

A software tool designed using the concepts of swarm intelligence and text mining is proposed as an aid in the analysis of free/open source software (FOSS) development communities. A prototype of the tool collects textual data from an electronic mailing list, a primary mode of FOSS developer communication. The tool enables a user to compare patterns of discussion topics found in the text with p...

Healthcare can be characterized as a complex adaptive system. New Zealand is recognized as having one of the highest rates of enmeshed clinical information and communication technology within this complex system. This paper describes the implementation of an integrated series of electronic clinical health knowledge management systems in a large New Zealand District Health Board. In combination ...

The literature contains research regarding how trust is formed in healthcare settings but rarely discusses trust formation in an emergent care population. A literature review was conducted to determine which of the trust determinants are important for this process as well as how to develop a scale to measure trust. A search generated a total of 155 articles, 65 of which met eligibility criteria...

Most theoretical perspectives used to explain the use and effects of communication and decision support technologies assume someform of technological a&rminism. lnwnsisten&s in the research jindings have prompted theorists to reject the assumptions of technological determinism in favor of an emergent perspective. To date, only adaptive structuration theo y CAST) offers the promise of satisfying...

Hydroxocobalamin is a recently approved antidote for the treatment of cyanide poisoning. The case presented involves a young patient administered empiric hydroxocobalamin due to suspected cyanide overdose. Due to the development of acute kidney injury and severe metabolic derangement, emergent hemodialysis was initiated. Unfortunately, hemodialysis was confounded by a recurrent "blood leak" ala...

Distributed applications are being deployed on ever-increasing scale and with ever-increasing functionality. Due to the accompanying increase in behavioural complexity, selfmanagement abilities, such as self-healing, have become core requirements. A key challenge is the smooth embedding of such functionality into our systems. Natural distributed systems such as ant colonies have evolved highly ...

As an emergent field of research and practice, the management of information and communication technologies (ICT) offers complex challenges, such as how to structure and organize the accumulated body of knowledge as well as the need to orchestrate and encapsulate theoretical perspectives and methodologies. As in any emergent field, the ICT management (ICTM) body of knowledge has mostly expanded...

OBJECTIVES To define and assess 'Consumer Health Informatics' and related emergent issues in an era of new media and of personalisation of care, and from this to define what actions need to be taken to optimise benefits and address risks. METHODS Definition of key concepts; review of health personalisation, emergent health information and communication technologies and knowledge sources avail...