OBJECTIVES Regular physical exercise is known to protect endothelial integrity. It has been proposed that acute exercise-induced changes of the (anti-)oxidative system influence early (glycocalyx shedding) and sustained activation (shedding cells, ECs) as well endothelial-cell repair by circulating hematopoietic stem progenitor cells (HPCs). However, results are not conclusive data in trained p...

Regenerative Vascular Tissue Engineering In article number 2200050, Quinton Smith and co-workers review strategies for regenerative vascular tissue engineering. The vasculature is a conduit that links various organ systems, guiding development, homeostasis, regeneration. They reflect in this cover the ability of cells (green endothelial cells) to self-assemble interact with parenchymal (red, st...

Objective(s)Metformin is well known for activation of AMP-activated protein kinase (AMPK). AMPK activation inhibits mammalian target of rapamycin (mTOR) as a key signaling process in cell proliferation. Recent epidemiological studies demonstrate that metformin lowers the risk for several types of cancer in diabetic patients. Concerning the critical role of angiogenesis in the incidence and prog...

This article refers to:RETRACTED ARTICLE: Cu(II)-organic framework for selective CO2/N2 separation and protective effect on hypertensive disorders with pregnancy via reducing the TNF-α VACM-1 expression in vascular endothelial cells

Vascular calcification is the abnormal deposition of calcium phosphate complexes in blood vessels, which regarded as pathological basis multiple cardiovascular diseases. The flowing exerts a frictional force called shear stress on vascular wall. Blood vessels have different hydrodynamic properties due to discrepancies geometric and mechanical properties. disturbance flow bending area branch poi...

SARS-CoV-2 was firstly found in bronchoalveloar lavage (BAL) of three suspected COVID-19 patients at Jinyintan Hospital, Wuhan, Hubei Province, China. The cases are still raisingwith2,12% global mortality rate. Hypoxic respiratory failure due to acute distress syndrome (ARDS) is the main cause death. Endothelial cell damage has an important role pathogenesis ARDS and multi-organ dysfuntion pati...

To assess different effects of royal Jelly in protecting the human endothelial cells from high glucose level, human umbilical vein endothelial cells were exposed to various concentrations of royal jelly, from 0.625 to 10 mg/ml, at the presence of 5 and 30 mM glucose contents over a course of 72 h. In addition to cell viability assessment by conventional MTT assay, we also analyzed the feature o...

objective(s) the aim of this study was to investigate glycoconjugates distribution patterns as well as their changes during the course of pituitary portal vasculogenesis and angiogenesis. materials and methods formalin fixed paraffin sections of 10 to 20 days of sprague dawly rat fetuses were processed for histochemical studies using four different horseradish peroxidase (hrp) conjugated lectin...