In Ontology-Based Data Management (OBDM), an abstraction of a source query q is over the ontology capturing semantics in terms concepts and relations available ontology. Since perfect characterization may not exist, notions best sound complete approximations have been introduced studied typical OBDM context, i.e., case where expressed DL-Lite, queries are as unions conjunctive (UCQs). Interesti...

High throughput RNA sequencing (RNA-Seq) allows for the profiling of thousands transcripts in multiple samples. For analysis generated RNA-Seq datasets, standard and well-established methods exist, which are however limited by (i) high dimensionality data with most expression profiles being uninformative, (ii) an imbalanced sample-to-feature ratio. This complicates downstream analyses these dat...

The aim of the current study was to identify gene signatures during the early proliferation stage of wound repair and the effect of TGF‑β on fibroblasts and reveal their potential mechanisms. The gene expression profiles of GSE79621 and GSE27165 were obtained from GEO database. Differentially expressed genes (DEGs) were identified using Morpheus and co‑expressed DEGs were selected using Venn Di...

Introduction: Nasopharyngeal carcinoma (NPC) is an endemic cancer in southern China, particularly Guangdong population, but the prognosis of NPC poor. Recently microRNA (miR) has been shown to have function aiding treatment cancer. Thus, this study, miRNAs and genes associated with were analyzed. Methods: mRNA-sequencing miR-sequencing data obtained from Gene Expression Omnibus. The differentia...

Abstract Background Obesity associated type 2 diabetes mellitus is a metabolic disorder ; however, the etiology of obesity remains largely unknown. There an urgent need to further broaden understanding molecular mechanism in mellitus. Methods To screen differentially expressed genes (DEGs) that might play essential roles mellitus, publicly available expression profiling by high throughput seque...