Crohn's disease (CD) is driven by seemingly aberrant immune responses directed toward commensal enteric microflora. However, the specific antigens targeted by this immune response remain largely undefined. Herein, we demonstrate that common enteric flagellins are one such target of the CD-associated immune response. Thus flagellin may not only drive acute inflammation via activation of Toll-lik...

The antimicrobial effects of aqueous garlic extracts are well established but those of garlic oil (GO) are little known. Methodologies for estimating the antimicrobial activity of GO were assessed and GO, GO sulfide constituents, and garlic powder (GP) were compared in tests against human enteric bacteria. Test methodologies were identified as capable of producing underestimates of GO activity....

BACKGROUND No studies so far have examined enteric infections in patients undergoing bone marrow transplantation (BMT) in developing countries where asymptomatic carriage and colonization with enteric pathogens is frequent. METHODS A prospective study followed 65 patients who underwent BMT in South India between 1995 and 1998. Patients were screened for enteric pathogens before transplantatio...

The correlation between Gram negative enteric rods and Porphyromonas gingivalis in periodontal diseases has received little attention in the literature. The objective of this study was to investigate the association between gram negative enteric rods and Porphyromonas gingivalis and changes in clinical parameters in chronic periodontitis subjects. Occurrence of Gram negative enteric rods, Porph...

diarrheal diseases can be caused by viral, bacterial and parasitic infections. this paper provides a preliminary image of diarrhea with regards to etiology and epidemiologic factors in tunisian children less than five years of age.overall, 124 diarrhoeal stools were collected from patients suffering from acute diarrhea and 54 stool samples from healthy children. all stools were examined for the...

Acute gastroenteritis (AGE) has a great impact on children less than five years of age, producing high levels of morbidity and mortality. Worldwide, AGE is mainly related to viruses, mainly rotavirus but human adenovirus (HAdV) in particular as an important etiologic agent. Among HAdV species F, genotypes 40 and 41 are responsible for a high number of diarrhea cases, mainly in children under 2 ...

Yersinia ruckeri is a pathogen that has an impact on aquaculture worldwide. The disease caused by this bacterial species, yersiniosis or redmouth disease, generates substantial economic losses due to the associated mortality and veterinary costs. For predicting outbreaks and improving control strategies, it is important to characterize the population structure of the bacteria. The phenotypic an...

Hirschsprung disease, or congenital megacolon, is characterized by aganglionosis of the terminal bowel, which leads to intestinal obstruction and chronic constipation. Several genes involved in the disease have been identified. In particular, haploinsufficiency of SOX10, which encodes a transcription factor, results in megacolon, often in combination with other disorders. Although Hirschsprung ...

T he importance of zoonotic enteric disease transmission at animal exhibit settings has become apparent in recent years, as outbreaks associated with animal exhibits are reported with increasing frequency. Until recently, awareness of direct animal-to-human transmission of enteric pathogens was limited; there had been a few individual case reports. 1-3 With recent large outbreaks associated wit...