The ascidian Ciona intestinalis, commonly known as a 'sea squirt', has become an important model for embryological studies, offering a simple blueprint for chordate development. As a model organism, it offers the following: a small, compact genome; a free swimming larva with only about 2600 cells; and an embryogenesis that unfolds according to a predictable program of cell division. Moreover, r...

3) 臨床経過 主訴:腹部膨満感,便通異常,粘液便. 既往歴:約30年間,心療内科に通院し抗精神病薬な どを服用している.その他に既往症はない. 現病歴:銅管の脱脂洗浄のため,2011年4月よりト リクロロエチレンを使用し始めたが,その2年半後の 2013年秋に便秘気味になり,その後,腹部膨満感があ り,ガスがよく出てトイレが近くなり,粘液も出るよう になった.同年12月に来院したため,腹部CT検査およ び超音波検査を実施した.その後も症状が続き,2014 年5月に来院したため,大腸内視鏡検査を実施した. 腹部CT検査:2013年12月の腹部CT検査では,上行 結腸に複数の憩室が認められた. 超音波検査:2013年12月の超音波検査では,強い腸 管内ガスエコーが認められた. 大腸内視鏡検査:2014年5月の大腸内視鏡検査では, 回盲部,上行結腸,S状結腸,上部直腸において多数の 粘膜...

The influence of ambient water quality on the settlement of barnacles and the green alga Enteromorpha spp. to an artificial substratum in the estuaries of Sydney, Australia, was investigated to test the efficacy of both groups of organisms as indicators of changes in water quality due to urban stormwater runoff and/or sewage overflows. Wooden settlement panels were immersed for 4 months on 17 o...

The objective of this study conducted in 75 herds was to investigate the presence and significance of Criptosporidium parvum and Giardia intestinalis in Swedish dairy calves in comparison with rotavirus, coronavirus and Escherichia coli K99+. The farmers were asked to collect faecal samples from each heifer calf that had diarrhoea between birth and 90 days of age, and also from a healthy calf o...

Deuterostome invertebrates possess complement genes, and in limited instances complement-mediated functions have been reported in these organisms. However, the organization of the complement pathway(s), as well as the functions exerted by the cloned gene products, are largely unknown. To address the issue of the presence of an inflammatory pathway in ascidians, we expressed in Escherichia coli ...

The use of the tunicate Ciona intestinalis as a model system to study the relationship between regeneration and aging is reviewed. Ciona has powerful regeneration capacities, which fade with age. Some additional benefits are-, a relatively short life span, the ability to study regeneration in vitro, the close phylogenetic relationship between tunicates and vertebrates, and the host of molecular...