Sodium valproate (SV) is effective and well tolerated for the treatment of epilepsy and mood disorders. There are several cases of SV-induced enuresis noted in epileptic patients. No alternative medication has been suggested to manage this problem. We present the first case of a pediatric bipolar patient who developed diurnal and nocturnal enuresis during SV therapy. Clinicians should be aware ...

conclusions there is no significant difference between monotherapy with desmopressin, imipramine or oxybutynin in children with enuresis. however, oxybutynin showed a higher response rate and a lower relapse rate compared to other medications. more clinical trials with a larger sample size are needed to clarify these uncertainties. results children in the oxybutynin group showed a slightly high...