introduction: the coagulation factor 13 has a fundamental role in homeostasis, protective effects on thrombosis, and some other associated diseases. due to increasing the chronic coagulability of major thalassemic patients, this study was conducted with aim determining the prevalence of val34leufxiii polymorphism in the thalassemic patients. materials and methods: the present case-control study...

Placental, immune and genetic factors are thought to play an important role in preeclampia (PE)'s pathophysiology. Angiotensin-Converting Enzyme (ACE) plays a vital role in the renin-angiotensin-system (RAS) which regulates blood pressure by converting angiotensin I into a powerfull vasoconstrictor angiotensin II. A deletion polymorphism (D allele) has been reported to be associated with elevat...