Three cases are reported of primary bronchial carcinoma with metastatic deposits in an intracranial glioma (two cerebral astrocytomas and one fourth ventricle ependymoma). The rarity of this phenomenon is emphasised and the literature critically reviewed.

Although it is quite rare, second primary neoplasms in cancer patients may present with the signs and symptoms of malignant spinal cord compression. Primary spinal cord tumours in the cancer patients may be deceptive and considered as the recurrent first cancer. Therefore, it should be precisely differentiated and appropriately managed. We report such a case of intramedullary ependymoma of the ...

Ependymomas usually develop from neuroectodermal organs. Here, we present an ependymoma arising from the pelvic cavity. A 27-year-old Korean female was admitted to the hospital with a sensation of abdominal fullness. Imaging studies revealed a huge heterogeneous nodular mass in the pelvis and lower abdomen. Laparotomy showed that two large masses with multiple nodules were located between the u...

OBJECT Cyclooxygenase-2 (COX-2), also known as prostaglandin endoperoxide synthase, has been reported to play an important role in the tumorigenicity of many types of tumors. The expression of COX-2 in spinal ependymomas, however, has not been studied. The authors evaluated COX-2 expression in ependymoma of the spinal cord. METHODS Sixteen ependymoma samples obtained in patients undergoing su...

Keywords Disease name Definition Diagnostic criteria and differential diagnosis Etiology Genetics Clinical description Prognosis Diagnostic methods Epidemiology Management Unresolved questions References Abstract Ependymoma accounts for 10% of all pediatric central nervous system tumors and originates in ventricular spaces or from residual intra-parenchymal ependymal cells. The most common loca...

PURPOSE To analyze the association between Ki-67 and eNOS expression with the pathological grades of patients with intracranial ependymomas, and to determine its value in distinguishing the progression of the disease. METHODS A clinicopathological study was undertaken in 82 patients with intracranial ependymomas. Tissue samples, obtained by tumour resection, were divided into three groups: lo...

BACKGROUND Ependymoma is a glial tumor that occurs in the central nervous system. The intradural extramedullary location of this neoplasm is very rare. The authors report a case of spinal intradural extramedullary ependymoma in a male and discuss its pathogenesis as well as its clinical, radiological, and therapeutical features. CASE DESCRIPTION A 31-year-old man was admitted at the author's ...

To cite: Crawford JR, Newbury RO, Friedman JR. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-010267 DESCRIPTION A 15-year-old girl with a history of congenital nystagmus presented with newly recognised hyperkinetic tongue movements on protrusion without dysphagia, dysphonia or palatal myoclonus (see online supplementary video). Contrast-enhanced MRI reveal...

Summary of Background Data: Five cases of hemorrhage into a spinal neoplasm after spinal or epidural anesthesia are reported in the literature. Presentation ranges from severe low back pain to acute cauda equina syndrome. Methods: A case study of a patient who hemorrhaged into an intradural, extramedullary spinal cord mass was performed. A detailed literature review is also provided. Results: A...

DWI reportedly accurately differentiates pediatric posterior fossa tumors, but anecdotal experience suggests limitations. In 3 years, medulloblastoma and JPA were differentiated by DWI alone in 23/26 cases (88%). Ependymoma (n = 5) could not be reliably differentiated from medulloblastoma or JPA. A trend toward increased diffusion restriction in higher grade tumors (1/14 grade I, 7%; 9/12 grade...