It is argued that as the major occupational cancer risks become matters of historical interest, research epidemiologists working in the field should broaden their approaches to encompass life style factors. In the investigation of possible low-cancer risks, it no longer makes any sense to confine their data-collecting activities solely to exposure to dusts and chemicals at work and to regard ex...

The application of genotyping to clinical isolates of Cryptosporidium has increased significantly our knowledge and understanding of the distribution and epidemiology of this parasite. However, some methods can be laborious and demand specialist technical expertise. PCR-restriction fragment length polymorphism (RFLP) techniques represent a more rapid and simple method of genotyping to support e...

The presently accepted method for marking individual strains of Staphylococcus aureus for epidemiological investigation is bacteriophage typing. However, phage typing is not a stable marker and many strains cannot be successfully typed. Serological typing is not readily available and preparation of sera is difficult. The aminopeptidase profile method described by Krawezyk and Huber was used to ...

BACKGROUND There is accumulating evidence from the epidemiological field of telomere biology that telomere length plays an important role in the pathophysiology of cardiovascular disease. The RNA-dependent DNA polymerase, telomerase, is essential in regulating telomere length by acting as a reverse transcriptase. However, the relationship between telomerase activity and telomere length in cardi...

BACKGROUND Occurrence of psoriasis has been found to be strongly genetically controlled in Northern European and U.S. twin and family studies. OBJECTIVE Our purpose was to assess cumulative incidence and heritability of psoriasis in the Australian population. METHODS Australian twins reporting psoriasis on a screening questionnaire received from 3808 pairs were mailed a detailed instrument ...

While multiple studies have shown that a woman’s control over land is positively associated with bargaining power outcomes, few have succeeded in highlighting successful methods for increasing this control. We report on a policy experiment in an unplanned settlement in Dar es Salaam, Tanzania, that provided access to formal land titles to informal settlers at randomized prices, with additional ...

OBJECTIVES To assess whether public health nurses adhered to Dutch guidelines for tuberculosis contact investigations and to explore which factors influenced the process of identifying contacts, prioritizing contacts for testing and scaling up a contact investigation. METHODS A multiple-case study (2010-2012) compared the contact investigation guidelines as recommended with their use in pract...

OBJECTIVE Area 7 of the autonomous region of Madrid has one of the highest incidences of tuberculosis (23/100,000 population per year 2004). This study aimed to identify tuberculosis control in this area. METHODS A descriptive study of tuberculosis cases diagnosed in area 7 from January 1, 1999 to December 31, 2004 was carried out by analyzing the incidence of tuberculosis and the management ...

In clinical research, questionnaires are an important tool available for population and large family studies to gather information on a patient’s medical history. In 1989, we described a large kindred of FrenchCanadian descent with an 8-fold increased risk of venous thrombosis due to the 3363C insertion in the protein C gene [1]. We developed a questionnaire for use in this family to assess gen...