BACKGROUND/AIMS Several rescue therapies have been recommended to eradicate Helicobacter pylori infection in patients with a failure of first-line eradication therapy, but they still fail in more than 20% of cases. The aim of this study was to evaluate the efficacy and safety of levofloxacin, metronidazole, and lansoprazole (LML) triple therapy relative to quadruple therapy as a second-line tre...

background the use of quadruple therapy for helicobacter pylori ( h. pylori ) eradication is a highly efficacious, gold standard regimen. however, according to a num­ber of studies, this regimen has numerous compliance problems and adverse effects. in the current study we have evaluated the h. pylori eradication rate following a quadruple therapy that included omeprazole, bismuth subcitrate, am...

In 2000 and 2001 there were 265 and 268 virologicallyconfirmed polio cases respectively, in India. In 2002 the number increased to 1,600. In response to some questions raised by the author (1), Dr Jay Wenger, project manager of the National Polio Surveillance Project of the WHO (NPSP-WHO), stated: “...the outbreak of 2002 and the problems of polio eradication were not caused by the failure of O...

BACKGROUND/AIMS Retreatment after initial treatment failure for Helicobacter pylori is very challenging. The purpose of this study was to evaluate the efficacies of moxifloxacin-containing triple and bismuth-containing quadruple therapy. METHODS A total of 151 patients, who failed initial H. pylori treatment, were included in this retrospective cohort study. The initial regimens were standard...

Helicobacter pylori infection is highly prevalent, affecting approximately half of the world's population. While the majority of infected individuals are asymptomatic, H. pylori infection is associated with certain diseases, including peptic ulcers (either duodenal or gastric), gastritis, and 2 malignancies-gastric cancer and gastric mucosa-associated lymphoid tissue lymphoma. Many of the epide...

To clarify the clinical efficacy of a single oral 2 g dose of azithromycin extended-release for heterosexual male patients with urethritis, and the current antimicrobial sensitivity of Neisseria gonorrhoeae to azithromycin, a prospective clinical trial was conducted from 2011-2013. In patients with gonococcal urethritis, the eradication rate was 90.9% (30 of 33). The susceptibility rates of iso...

BACKGROUND AND AIMS Failure in the eradication of H. pylori is a frequent occurrence. We assessed the effectiveness of a third-line, levofloxacin-containing, 10-day sequential treatment, in order to obtain eradication of H. pylori resistant patients in a clinical setting. METHODS One-hundred and nineteen consecutive patients with proven two consecutive failures in curing H. pylori infection, ...

Helicobacter pylori is a widespread disease causing most of the peptic ulcer diseases and low-grade mucosa-associated lymphoreticular tissue (MALT) lymphoma. Moreover, H. pylori is a proven environmental risk factor for gastric carcinoma and it has been recognized as a type 1 carcinogen factor. A combination of drugs has been proposed, using a proton pump inhibitor (PPI), amoxicillin, clarithro...

background: association between helicobacter pylori (hp) infection and migraine and the effect of hp eradication on relief of migraine headache have been studied but the results are controversial. objectives: to evaluate the effect of hp eradication in treatment of patients affected by migraine. materials and methods: eighty consecutive hp infected patients affected by migraine without aura wer...

Background In order to mitigate potential issues with antibiotic resistance in the treatment of patients with Helicobacter pylori infection, the selection of a therapeutic regimen is optimized by being aware of local eradication rates as well as the patient's medication history and previous diagnoses. Purpose This study primarily aimed to calculate the eradication rate of H. pylori infection ...