In the assessment of the patient with erectile dysfunction, psychogenic and organic (vascular, neurological and endocrine) involvement should be considered in the pathogenesis of the condition. The possibility of erectile dysfunction being of mixed origin, complicates the diagnostic approach even further. An integrated team approach of different specialists is required. In our Sex Institute, ev...

INTRODUCTION The Men's Attitudes to Life Events and Sexuality (MALES) study assessed the prevalence and correlates of erectile dysfunction, and examined men's attitudes and behavior in relation to this dysfunction. AIM To report on the attitudes of men, with and without self-reported erectile dysfunction, concerning masculine identity and quality of life. METHODS The MALES Phase I study inc...

OBJECTIVE  To estimate the risk of erectile dysfunction in men who used 5-α reductase inhibitors to treat benign prostatic hyperplasia or alopecia. DESIGN  Cohort studies with nested case-control analyses. SETTING  UK Clinical Practice Research Datalink. POPULATION  Two populations of men free of risk factors for erectile dysfunction and other sexual dysfunction or its treatment: men aged...

BACKGROUND In a group of 22 patients with erectile dysfunction, vasculogenic, neurogenic, endocrinologic or psychogenic investigations failed to find a cause for their erectile dysfunction. The electro-cavernosograms of these patients recorded a diminished activity. We investigated the hypothesis that diminished corpus cavernosum electromyography activity was the cause of erectile dysfunction i...

PURPOSE To understand the potential contribution of systemic endothelial dysfunction to diabetic erectile dysfunction, and the time course of erectile dysfunction in a streptozotocin (STZ)-induced diabetic rat model. MATERIALS AND METHODS Among 84, 12-week-old Sprague-Dawley rats, 48 rats received intraperitoneal STZ and were classified into six groups of diabetes by the period of observation...

Erectile dysfunction following radical prostatectomy for clinically localized prostate cancer is a known potential complication of the surgery. Because prostate cancer is diagnosed today more frequently than in the past and because the diagnosis is made in increasingly younger men, there is an urgent need to develop effective interventions that preserve erectile function after surgery. In this ...

PURPOSE Erectile dysfunction is a common problem, particularly in diabetics. It is associated with a considerable burden of suffering. No generally accepted drug treatment exists. We systematically reviewed and meta-analyzed all randomized, placebo controlled trials of yohimbine monotherapy for erectile dysfunction to determine its therapeutic efficacy. Our secondary aim was to evaluate the saf...