High preoperative serum midkine concentration is associated with poor survival in patients with esophageal cancer, even after radical surgery, and thus may have prognostic value. Midkine (MK), a heparin-binding growth factor, is expressed in numerous cancer tissues, and serum MK (S-MK) concentrations are increased in patients with various neoplasms. The aim of this study is to evaluate the clin...

Biomarker identification is crucial for the selection of patients who might benefit from radiotherapy. To explore potential markers for response and prognosis in patients with locally advanced esophageal carcinoma treated with radiotherapy followed by surgery, we evaluated the expression of cell cycle checkpoint-related proteins Chk2, Cdc25C, and Cyclin D1. A total of 56 patients with locally a...

OBJECTIVE The primary aim of this study was to test the widespread assumption that the viability of the gastric fundus is compromised by fundoplication, thereby limiting the use of stomach to reconstruct the upper gastrointestinal tract after esophageal resection. METHODS Between February 1991 and February 2006, a consecutive series of 142 patients with esophageal adenocarcinoma (EADC) underw...

1. Yue WM, Brodner W, Highland TR. Long-term results after anterior cervical discectomy and fusion with allograft and plating: a 5 to 11-year radiologic and clinical follow-up study. Spine (Phila Pa 1976). 2005;30:2138–44. 2. Baron EM, Soliman AM, Gaughan JP, Simpson L, Young WF. Dysphagia, hoarseness, and unilateral true vocal fold motion impairment following anterior cervical diskectomy and f...

BACKGROUND The management of esophageal discontinuity remains challenging and often involves complex reconstructive surgeries. METHODS AND RESULTS We describe a unique and successful treatment of esophageal discontinuity using a modification of the natural orifice translumenal surgery (NOTES) approach in a patient presenting with long-standing esophageal discontinuity resulting from an iatrog...

To investigate the role of Computer Tomography (CT) in the esophageal cancer surgery. 97 cases confirmed by pathology as esophageal cancer were retrospectively analyzed with preoperative Computer Tomography images and intraoperative situation. Tthe Computer Tomography can accurately display the thickness and length of the lesion segment esophageal wall, the relations between tumor and the aorta...

Ultrasonogram revealed cystic lesion in the right upper chest with internal echoes. Barium swallow showed a mass lesion causing smooth indentation of the esophageal outline (Fig. 1). At surgery, a cyst was identified in the posterior mediastinum, which was para-esophageal in location extending into the superior mediastinum. After excision, clinical improvement was rapid and child is well 8 mont...

Mastroianni et al. [1] report high prevalence (100%) of respiratory symptoms in their cohort of 19 children who received surgery for esophageal atresia. In contrast with the results of other studies [2], they found gastro-esophageal reflux incidence was low (26,3%). They therefore emphasize anti-reflux therapy could not be effective for treatment of respiratory symptoms in this group of patients.