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new derivatives of 2-[2-(2-chlorophenoxy)phenyl]-1,3,4-oxadiazole as candidates for agonistic effect on benzodiazepine receptors were synthesized. conformational analysis and superimposition of energy minima conformers of the novel compounds on estazolam, a known benzodiazepine agonist, revealed that the main proposed benzodiazepine pharmacophores were well matched. in pharmacological evaluatio...

In this paper, we proposed a new, highly scalable method to solve the database selection problem when the number of local databases in a metasearch engine is very large. For single-term queries, this method guarantees all desired documents to be retrieved. Experiments were conducted to show that this method is very eeective for typical short Internet queries. We also illustrated that the our da...

Inadequate pain relief after cardiac surgery increases morbidity and persistent post-sternotomy syndrome significantly, regional analgesia could improve control outcomes in surgery.1Deneuville M. Bisserier A. Regnard J.F. et al.Continuous intercostal with 0.5% bupivacaine thoracotomy: A randomized study.Ann Thorac Surg. 1993; 55: 381-385Abstract Full Text PDF PubMed Scopus (51) Google Scholar, ...

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