نتایج جستجو برای: esx
تعداد نتایج: 349 فیلتر نتایج به سال:
Mycobacterium tuberculosis EsxA and EsxB proteins are founding members of the WXG100 (WXG) protein family, characterized by their small size (approximately 100 amino acids) and conserved WXG amino acid motif. M. tuberculosis contains 11 tandem pairs of WXG genes; each gene pair is thought to be coexpressed to form a heterodimer. The precise role of these proteins in the biology of M. tuberculos...
Like several other intracellular pathogens, Mycobacterium marinum (Mm) escapes from phagosomes into the host cytosol where it can polymerize actin, leading to motility that promotes spread to neighboring cells. However, only approximately 25% of internalized Mm form actin tails, and the fate of the remaining bacteria has been unknown. Here we show that cytosolic access results in a new and intr...
The non-tuberculous Mycobacterium kansasii , is the causative agent of destructive pulmonary and extrapulmonary infections in immunocompromised persons. Incessant use multiple antibiotics lack effective vaccines did little to combat M. mediated infections. Here, a bioinformatic analysis has been carried out using PanExplorer, analyze pangenome aimed at functional characterization bacterium, und...
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