Presynaptic biogenic amine transporters mediate reuptake of released amines from the synapse, thus regulating serotonin, dopamine and norepinephrine neurotransmission. Medications utilized in the treatment of depression, attention deficit-hyperactivity disorder and other psychiatric disorders possess high affinity for amine transporters. In addition, amine transporters are targets for psychosti...

The increase in temperature caused by climate change is one of the greatest challenges wine industry has to face. Temperature affects sugar and alcohol content, which directly impact chemical organoleptic characteristics wine. This a serious on competitiveness profits companies sector. Among most studied strategies focused guaranteeing quality use yeast strains that are better adapted condition...

The interaction of the spike (S) glycoprotein SARS-CoV-2 with angiotensin-converting enzyme 2 (ACE2) correlates increased virus transmissibility and disease severity in humans. Two strategies may be considered for preventive or treatment purposes: blockage ACE2 receptors shielding receptor-binding domains (RBD) Sprotein COVID-19, as well S2 cleavage site that is used by furin host cells late ph...

  Some of fused dihydrobenzo [4,5]imidazo [1,2-a] pyrmido [5,4-e] pyrmidin-3(4H)-amine  derivatives were synthesized,  theses derivatives derived from 4-amino-2-(4-chloro or bromophenyl) -1,2-dihydropyrimido[1,2-a] benzimidazole-3-carbonitrile (4,5), which prepared by reaction 1H-benzimidazol-2-amine (1) and p-chlorobenzaldehyde p-bromobenzaldehyde (2)  and malononitrile (3)...

Abstract:  In this study adiffusion based mathematical model was developed to compare the performance of amine-grafted adsorbents with that of 13X zeolite in a fixed-bed adsorption tower which is used to capture CO2 from both humid and dry nitrogen stream under industrial conditions. The results show that the performance of amine-grafted adsorbent and 13X zeolite is almost the same in the dry ...

An analogous series of dimethylalkyl compounds, consisting of four amines, an amide, and a phosphonate ester, inhibited motility and reproduction of the nematode Caenorhabditis elegans. Dimethylamines with straight-chain lengths of 12, 14, or 16 carbon atoms were equally active nematicides, causing greater than 80% population growth inhibition at a concentration of 25 ppm. The C12 straight-chai...

AIMS To assess the potential bactericidal activity of amine oxide (C10-C16-alkyldimethyl N-oxides) against Streptococcus mutans grown as planktonic suspension and as biofilm on hydroxyapatite discs, and its ability to control acidification of the media. METHODS Amine oxide bacteriostasis was investigated using the Bioscreen C Microbiological Growth Analyser, while a standard suspension test w...