the objective of the present study was to prepare controlled release formulation of moxifloxacin hydrochloride ocular nanoparticles. the nanoparticles were prepared by solvent displacement method using eudragit rl 100 as a polymer. different formulations were prepared by varying the ratios of drug and polymer and varying the ratios of organic and aqueous phase. the formulations were evaluated i...

Objective: Sonneratia alba leaves were used by the community for traditional medicine to cure muscle pain, back antioxidants, rheumatism, malaria, wounds, tuberculosis (TB) and as a spermicide. S. extract was easy damage because of light exposure, change pH, weather long period storage time. The problem can be solved coating with microencapsulation technique. purpose this research formulate mic...

Three layered pellets of budesonide were prepared for colon delivery by the extrusion-spheronization method. The coatings consisted of hydroxypropylmethyl cellulose (HPMC) (as barrier layer), Eudragit E (as rate controlling layer) and hydroxypropylmethyl cellulose acetate succinate (HPMC AS) (as enteric layer). The rate controlling layer was further modified using various pore formers. Dissolut...

Gelatin-eudragit L100 nanoparticles of wet size range 170-563nm were prepared by two step dissolvation method and the effect of different concentrations of eudragit L100 and emulsifying agent sodium lauryl sulphate (SLS) on the particle size were studied. Synthesized nanoparticles were characterized by attenuated total reflectance-fourier transform infrared spectroscopy (ATRFTIR) and the mean s...

abstract: background: a new type of drug delivery system known as mucoadhesive film has been developed for oral thrush treatment. due to comfortable use of this drug delivery system, this would be encouragingly utilized, especially in babies and patient under chemotherapy. nystatin mucoadhesive film (nmf) is a polymeric film which is adhered to front upper gum and back to the upper lip and rele...

the most frequent adverse effects of indomethacin like other nsaids are gastro–intestinal and central nervous system disturbances. extended release or enteric release formulations minimize these symptoms. the objective of this study was to develop an extended release pellet formulation of indomethacin by the centrifugation (rotary fluid bed granulation) or powder layering method. layered, nonpa...