OBJECTIVE To analyse the use of health care resources and the associated costs in patients with rheumatoid arthritis (RA) treated with three biological disease-modifying anti-rheumatic drugs (bDMARDs): etanercept, infliximab and adalimumab. METHOD DESIGN observational, retrospective, multicentre study. Length of study: 6 months. TARGET POPULATION patients with RA, who have been undergoin...

Central bank credit has expanded dramatically in some of the euro area member countries since the beginning of the …nancial crisis. This paper makes two contributions to understand this stylized fact. First, we discuss a simple model of monetary policy that includes (i) a credit channel and (ii) a common pool problem in a monetary union. We illustrate that the interaction of the two elements le...

The aim of this systematic review was to collect and summarise all current data on the cost-effectiveness of biological treatment in ulcerative colitis. A literature search was conducted using the Medline, Embase, Centre for Reviews and Dissemination databases and included all cost-effectiveness analyses comparing biological treatment with any comparator. We identified 277 records of which 10 w...

This study reexamines the evidence for the Balassa-Samuelson effect for the 1985-2007 period. Cointegrating relationships between the real exchange rate and productivity, real price of oil and government spending are estimated using the Johansen and Stock-Watson procedures. The findings show that for each percentage point in the US-Euro area productivity differential there is a three percentage...

This paper investigates the effects of the various systems of tradeable allowances for CO2-emissions in the Netherlands. These effects are compared with those of raising and adapting the current energy taxes. The results show that a hybrid emissions system (with a absolute cap for sheltered sectors and a relative cap for exposed sectors) performs best in terms of a net national income measure o...

This study analysed the cost-effectiveness of four different treatment modalities (medical therapy, PTA with and without stent, and surgery) for the therapy of renal-artery stenoses in hypertensive patients in Germany. A computerised, predictive decision-analytic model, based on economic input data and the cost of medical care in Germany, and the results of published data from prospective clini...

This clinical study examined differences in wear in manual toothbrushes from different price categories. 140 volunteers (14 groups of 10) brushed twice daily for 2-3 minutes over a period of three or six months using the modified Bass technique and seven different toothbrushes (TB) from three price categories. A: 2 TB for under 1 Euro; B: 2 TB priced between 1 and 2 Euro; C: 3 TB priced at over...