OBJECTIVES Hypothermia and decompressive craniectomy (DC) have been shown to be neuroprotective. This study was designed to evaluate neuroprotective effects of delayed singular or combination of DC and local hypothermia on stroke. MATERIALS AND METHODS Cerebral ischemia was induced in 48 Wistar rats assigned to 4 groups: control, decompressive craniectomy (DC), local hypothermia (LH), combina...

Abstract. This research firstly aims to fabricate and characterize doped TiO2 nanoparticles (NPs) by iron Sulphur dopants, then the determination of photocatalytic activity NPs. Titanium tetraisopropoxide (TTIP), trichloride hexahydrate, thiouria, glacial acetic are utilized as precursors in hydrothermal method without using a template or surfactant. The synthesized NPs investigated X-ray diffr...

Channelrhodopsin-2 ectopically expressed in the retina can recover the response to blue light in genetically blind mice and rats, but is unable to restore visual function due to optic nerve or optic tract lesions. Long Evans rats at postnatal day 1 were used for primary culture of visual cortical cells, and 24 hours later, cells were transfected with recombinant adenovirus carrying channelrhodo...

Endocardial lesions are caused not only by inflammatory processes but also by myocardial ischemia, resulting in endocardial thrombosis and cerebral embolism. We deviced a method for direct visualization of endocardial damages by a novel dye image cardioscopy with Evans blue and examined its feasibility in patients with heart disease. The dye was injected into the left ventricle before and after...

Among the earliest recorded experiments on the tion of the blood volume are those of Bischoff (1856, 1858) and Weicker (1858), who by exsanguinationm directly the amount of blood obtained from the bodies of executed criminals. Since that time much genuity has been xrcised in devising methods of esimating blood volume which would conbine accuracy with ease of application to the living human subj...

BACKGROUND In previous studies, the neuroprotective effect of 17β-estradiol in diffuse traumatic brain injury has been shown. This study used ICI 182,780, a non-selective estrogen receptor antagonist, to test the hypothesis that the neuroprotective effect of 17β-estradiol in traumatic brain injury is mediated by the estrogen receptors. METHODS The ovariectomized rats were divided into eight g...

In order to test photoelectric recording of dye curves, simultaneous determinations of cardiac output were made in 48 patients with heart disease with the Fick and dye-dilution technics. The dye curves were recorded with a Colson densitometer following either intrathoracic or antecubital injection of dye. Both Evans blue and indoeyanine green dyes were employed. Satisfactory agreement was noted...

Objective(s):Hypothermia and decompressive craniectomy (DC) have been shown to be neuroprotective. This study was designed to evaluate neuroprotective effects of delayed singular or combination of DC and local hypothermia on stroke. Materials and Methods: Cerebral ischemia was induced in 48 Wistar rats assigned to 4 groups: control, decompressive craniectomy (DC), local hypothermia (LH), combin...