BACKGROUND Toxoplasmosis is an important, widespread, parasitic infection caused by Toxoplasma gondii. The chronic infection in immunocompetent patients, usually considered as asymptomatic, is now suspected to be a risk factor for various neurological disorders, including epilepsy. We aimed to conduct a systematic review and meta-analysis of the available literature to estimate the risk of epil...

The latent toxoplasmosis is usually considered to be asymptomatic, however, this paradigm has never been rigorously tested. Here we searched for symptoms of deterioration of physical health (decrease of weight) in infected people by analysis of clinical records of 758 women tested for toxoplasmosis in the 16th week of gravidity. Toxoplasma-positive women have a lower body weight in the 16th wee...

Background: Toxoplasmosis has a more severe manifestation in pregnant women and immunocompromised individuals. Up to 15% of immunocompetent individuals who have acquired the infection may be asymptomatic, however others symptoms confused with another cause manifestations such as ocular toxoplasmosis which is most common chorioretinitis can lead retinal necrosis. Considering that clinical charac...

BACKGROUND ROP16 is a protein kinase of Toxoplasma gondii identified in the mouse model as a virulent marker, but it is unknown whether this finding is relevant in human toxoplasmosis. METHODS We obtained the Toxoplasma ROP16 locus DNA sequence in samples from 12 patients with ocular toxoplasmosis, 1 sample from a patient with congenital toxoplasmosis, 22 samples from soldiers operating in th...

A large amount of research has been done on toxoplasmosis in the last 30 years, and the world-wide incidence of the infection, and its clinical manifestations, are recognized and documented in an extensive literature. New discoveries concerning the life-cycle of the organism (Frenkel, I970; Hutchison, Dunachie, Siim, and Work, I970) promise to solve many of the problems of the transmission of i...

BACKGROUND In immunocompetent patients, acute toxoplasmosis is usually asymptomatic. We identified M1 macrophages in a case of symptomatic acute Toxoplasma gondii infection that resolved without treatment. M1 macrophages have been demonstrated in animal models of toxoplasmosis, but not in humans. CASE PRESENTATION A 63-year-old woman presented with laterocervical and axillary bilateral lympha...

OBJECTIVE RhD-positive subjects are protected against toxoplasmosis-associated impairment of psychomotor performance. Here we searched for RhD-positivity-associated maternal protection against the effects of toxoplasmosis. METHODS In the present retrospective cohort study, we analysed data from 785 (139 RhD-negative) Toxoplasma-free and 194 (27 RhD-negative) Toxoplasma-infected pregnant women...

BACKGROUND Toxoplasmosis is becoming a global health hazard as it infects 30-50% of the world human population. Clinically, the life-long presence of the parasite in tissues of a majority of infected individuals is usually considered asymptomatic. However, a number of studies show that this 'asymptomatic infection' may also lead to development of other human pathologies. AIMS OF THE STUDY The...

OBJECTIVES To compare the results of magnetic resonance imaging (MRI) and thallium-201 (201Tl) SPET scanning with laboratory analyses including CSF DNA detection, brain biopsy, and necropsy in the discrimination of cerebral lymphoma and toxoplasmosis in patients with AIDS. METHODS A retrospective study of 32 patients infected with HIV who had focal CNS lesions on MRI as a result of either lym...

Abstract: Toxoplasmosis is a disease that identical to cats. This caused by the parasite Toxoplasma gondii. In this study, mathematical model of spread toxoplasmosis was reviewed with various population size. construction, fixed point analysis and parameter sensitivity were carried out. From analysis, it shown cat transmission rate from susceptible an infected (horizontal rate) probability born...