The critical study of one’s own family history is a relatively new field that sits at the intersection genealogical research and scholarly [...]

BACKGROUND AND PURPOSE The association between family history of stroke and stroke recurrence remains unclear. METHODS Using a web-based multicenter stroke registry database, information on history of stroke in first-degree relatives was collected prospectively for acute ischemic stroke patients who were hospitalized within 7 days of onset. The collected information was categorized as follows...

Electronic Health Record (EHR) systems are becoming highly prevalent today and have the potential to add to the success of spontaneous reporting systems for post marketing surveillance of drugs. EHR systems broadly contain two forms of information viz. coded (structured) information and unstructured text. Researchers have shown that the textual data have much more utility for cohort building th...

589 T HIS STUDY iS conceriled with the family history of 722 infants who were horn with spina bifida cystica (meningomyelocele, myelocele and meningocele) and who were referred to the Children’s Hospital, Sheffield, for surgical treatment. No cases were excluded from this investigation. None of the infants or children were referred for genetic advice hecautse of special problems, and if there w...

Double balanced translocations are particularly rare and the risk of a fetus with an unbalanced chromosomal anomaly is greater than for single translocation carriers. In this present case, we describe an interesting family history which included three generations. A couple, married for 4 years, was referred to the genetic clinic due to infertility and family chromosome anomalies. A GTG-band chr...

Asperger syndrome (AS) is a childhood-onset disorder often described as a mild variant of autism. Although classified as a distinct disorder in the DSM-IV, its overlap with autism continues to be a matter of ongoing debate. While the family genetic origins of autism are well established, few studies have investigated this topic in AS using current operational criteria. In this report, we examin...