Commentary: The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension. Pulmonary arterial hypertension (PAH) is a progressive and irreversible lung disease that reduces survival. Importantly, the pulmonary arteries carry blood from the heart to the lungs; however, in PAH pulmonary vessels are remodeled causing abnormal constriction and a pressure change that pr...

The TEL/AML1 fusion associated with t(12;21)(p13;q22) is the most common gene rearrangement in childhood leukemia, occurring in approximately 25% of pediatric acute lymphoblastic leukemia (ALL), and is associated with a favorable prognosis. For example, a cohort of pediatric patients with ALL retrospectively analyzed for the TEL/AML1 fusion treated on Dana-Farber Cancer Institute (DFCI) ALL Con...

Rüveyda Dok, Peter Kalev 3, , Evert Jan Van Limbergen , Layka Abbasi Asbagh, IriaVázquez 2, , Esther Hauben , Anna Sablina , Sandra Nuyts 5 KU Leuven, University of Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, 3000 Leuven, Belgium KU Leuven, University of Leuven, Department of Human Genetics, Laboratory for Mechanisms of Cell Transformation, 3000 Leuven, Belgium 3 VI...

1996;109;312-315 Chest Galassetti and Felice Manfredi Edward T. Mannix, Mark O. Farber, Paolo Palange, Pietro Skaters Exercise-Induced Asthma in Figure http://chestjournal.chestpubs.org/content/109/2/312 and services can be found online on the World Wide Web at: The online version of this article, along with updated information ISSN:0012-3692 ) http://chestjournal.chestpubs.org/site/misc/reprin...

Paratanais rosadi sp. n. described from Puerto Rican coastal waters represents the first species of the genus from the northwestern Atlantic. It is distinguished from the other Paratanais species by a combination of characters, including article-2 of the maxilliped palp with a geniculate, finely-serrulate seta on inner margin; chela with stiff, geniculate, seta arising from propodus between fix...

A new species of the hermit crab genus Diogenes Dana, 1851 (Diogenidae), D. canaliculatus, is described and illustrated on the basis of material from off the Kerala State, southern India. It is referred to the D. edwardsii (De Haan, 1849) species group, and compared with D. bicristimanus Alcock, 1905, D. fasciatus Rahayu & Forest, 1995, D. laevicarpus Rahayu, 1996 and D. moosai Rahayu & Forest,...

From the Laboratory of Neurogenetics and Pathobiology, Laboratory of Neurodegenerative Diseases and Gene Discovery, Farber Institute for Neurosciences, Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, and the **Department of Neurobiology and Behavior, State Universi...

A novel multi-network approach reveals tissue-specific 1 cellular modulators of fibrosis in systemic sclerosis, 2 pulmonary fibrosis and pulmonary arterial hypertension 3 4 Jaclyn N. Taroni, Casey S. Greene, Viktor Martyanov, Tammara A. Wood, Romy B. 5 Christmann, Harrison W. Farber, Robert A. Lafyatis, Christopher P. Denton, Monique E. 6 Hinchcliff, Patricia A. Pioli, J. Matthew Mahoney§, Mich...

1Indiana University Simon Cancer Center, Indianapolis, IN; 2Dana-Farber Cancer Institute, Boston, MA; 3North Division of Montefiore Medical Center, Bronx, NY; 4Mayo Clinic, Rochester, MN; 5University of Rochester, Rochester, NY; 6Rambam Medical Center, Haifa, Israel; 7Case Comprehensive Cancer Center, Cleveland, OH; 8University of Pennsylvania, Philadelphia, PA; and 9Memorial Sloan-Kettering Ca...