Human fascioliasis (HF), caused by the common liver fluke Fasciola hepatica, is an endemic infection in many parts of tropical countries. HF can also be seen in some of the non-tropical countries. This report describes two girls with severe iron deficiency anemia and eosinophilia, who were diagnosed as HF. The infection was successfully eliminated with the administration of triclabendazole. No ...

Fasciola hepatica infestation is known to cause bile duct inflammation and biliary obstruction. Endoscopic retrograde cholangiopancreatography shows distinct features in some patients with fascioliasis, but the condition may be overlooked in chronic cases. The endoscopic retrograde cholangiopancreatograpy images must be carefully examined to rule out other possible causes of irregularity and th...

Este estudio se llevó a cabo para establecer la prevalencia e identificar los factores de riesgo asociados con las infestaciones por tremátodos en ganado lechero Holstein el valle Paipa-Boyacá. Las muestras fecales recogidas 100 bovinos seleccionados aleatoriamente examinaron utilizando una técnica sedimentación simple recuento diferencial huevos tremátodos. Se buscaron tres grupos tremátodos, ...

The efficacy of the 5-chloro-2-methylthio-6( 1 n a p t h y l o x y ) 1H-benzimidazole called compound alpha, formulated as boluses or suspension, was evaluated against adult Fasciola hepatica in cattle. Twenty-seven steers were infected, each with 600 metacercariae of F. hepatica. After 10 weeks of infection, the animals were divided into 3 groups of 9 animals each. Group 1 received boluses at ...

OBJECTIVES The pharmacokinetic (PK) parameters of artesunate, recently discovered to possess promising trematocidal activity, and its main metabolite dihydroartemisinin (DHA) were determined in rats infected with hepatic and biliary stages of Fasciola hepatica and compared with uninfected rats after single intragastric and intravenous (iv) doses. METHODS Rats infected with F. hepatica for 25 ...

Anthelmintic resistance (AR) to Fasciola hepatica is emerging worldwide. Recently, AR to the adulticide compound albendazole (ABZ) was shown in Argentina and Spain. In Sweden, ABZ treatment failure against F. hepatica was first reported in sheep in 2012. The present study tested the efficacy of ABZ and triclabendazole (TCBZ) in sheep naturally infected with F. hepatica using a combination of th...

Red deer (Cervus elaphus) are hosts of liver fluke (Fasciola hepatica); yet, prevalence is rarely quantified in wild populations. Testing fresh samples from remote regions by faecal examination (FE) can be logistically challenging; hence, we appraise frozen storage and the use of a coproantigen ELISA (cELISA) for F. hepatica surveillance. We also present cELISA surveillance data for red deer fr...

El estudio se llevó a cabo para establecer la prevalencia e identificar los factores de riesgo asociados con las infecciones por trematodes en ganado lechero tierras altas Boyacá, Colombia. Las muestras fecales recogidas 300 bovinos seleccionados al azar examinaron utilizando una técnica sedimentación simple el recuento diferencial huevos trematodes. En estudiado fueron encontrados tres grupos ...